Avetikov D. S., Lokes K. P., Ivanytska O. S., Pronina O. M., Pliak O. A.
THE INFLUENCE OF PRF AND PRP TECHNOLOGIES ON THE PROCESSES OF REPAIR AND EPITHELISATION OF POST-EXTRACTION WOUNDS
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About the author:
Avetikov D. S., Lokes K. P., Ivanytska O. S., Pronina O. M., Pliak O. A.
Heading:
DENTISTRY
Type of article:
Scientific article
Annotation:
The article is devoted to the establishment and study of clinical indicators of post-extraction wound repair against the background of the action of PRF-folds and PRP injections into the peri-alveolar tissues. The purpose of the study was to increase the effectiveness of surgical treatment during tooth extraction by using a modified method of intraand postoperative prevention of complications with the use of PRF injected into the post-extraction wound in combination with PRP injections. Material and methods of the study. 60 patients participated in the study. Patients were monitored on the 1st, 3rd, 7th, and 10th day after the surgery. On the 5th day, the area of epithelialization was additionally measured. In the first clinical group, they averaged 5.2±0.4 points. In the second and third clinical groups, this indicator was slightly higher and amounted to 5.4±0.4 and 5.5±0.6 points, respectively. On the third day, the dynamics of the indicators changed slightly, namely in group 1 this indicator was 2.6±0.3, in groups 2 and 3 it was 2.4±0.4 and 2.2±0.4. On the 5th day of observation of patients in groups 2 and 3, positive dynamics were observed, especially in patients in group 3, the pain index on the MLS scale was 0.8±0.3, in contrast to 1.1±0.4 and 1.6±0.4, respectively, in the second and first clinical groups. It has been proven that with the combined use of PRF and PRP, moderate edema with barely noticeable peripheral hyperemia is observed in patients in the 3rd clinical group on the 3rd day. It is worth noting the changes on the 7th day of the postoperative period: unlike the 2 previous groups, in patients of the 3rd group, we did not detect any visualized edema, hyperemia, or signs of inflammation, and on the 10th day, in 80% of cases, we recorded the final stage of the wound epithelialization process, without subjective complaints from patients.
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Bibliography:
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Publication of the article:
«Bulletin of problems biology and medicine», 2024 Issue 4, 175, 645-651 pages, index UDC 616.716-006-074
