Ankin M. L., Akhmad F. M.

PREDICTING THE RISK OF PREOPERATIVE DEEP VEIN THROMBOSIS IN PATIENTS WITH PROXIMAL FEMORAL FRACTURE

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About the author:

Ankin M. L., Akhmad F. M.

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CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

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Preoperative deep vein thrombosis (DVT) is one of the most serious complications in patients with femoral fracture, which can affect the surgery timing. Current research has focused mainly on the study of risk factors and the effectiveness of postoperative DVT management, while trials investigating preoperative DVT are rare. The study included 88 (20 men, 68 women) patients with proximal femoral fracture aged 29 to 98 years (average age 72.97±13.17 years), among whom 27 cases of DVT were diagnosed by duplex ultrasound of the lower extremities before surgery, which was 30.7%. These 27 patients with preoperative DVT constituted group I; group II included 61 individuals without thromboembolic complications before surgery. The analysis of the relationship between preoperative DVT and clinical characteristics of patients was performed using univariate and multivariate regression analysis. The most common risk factors for preoperative DVT in the setting of proximal femoral fractures are: female patients, individual anamnesis of VTE, severe pulmonary disease, VTE family history, lower extremity venous disease, osteoporosis, lower extremity inflammation. Significant risk factors for preoperative VTE in patients with proximal femoral fractures were found to be a Caprini thrombosis risk score of >10 and an increase in the time from injury to surgery of >6.5 days. The obtained results may be used to improve preoperative assessment algorithms for patients with proximal femoral fractures. The application of the identified criteria may facilitate timely diagnosis of venous thrombosis and optimize the strategy of preoperative preparation for surgical treatment. The Caprini VTE risk score and the preoperative waiting time are independent predictors of the preoperative DVT development, with an increase of one unit of measurement increasing the risk of thrombosis by 1.485 times (95% CI [1.075–2.051], p=0.016) and 1.166 times (95% CI [1.001–1.357], p=0.048), respectively.

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Publication of the article:

«Bulletin of problems biology and medicine», 2026 Issue 3, 182, 199-205 pages, index UDC 616.718.4:616-001.5(477)

DOI:

10.29254/2077-4214-2026-3-182-199-205