Mitelov D. A., Mykhailova I. A., Perepolkina A. I.

MENTAL DISORDERS IN ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS DURING THE WAR

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Mitelov D. A., Mykhailova I. A., Perepolkina A. I.

Heading:

PEDIATRICS

Type of article:

Scientific article

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Global military conflicts consistently trigger a cascade of changes across political, economic, and social domains. Furthermore, they exert both direct and indirect impacts on public health; among the civilian population, the elderly, children, and adolescents constitute the most vulnerable cohorts. Factors of warfare including explosions, destruc tion of housing, UAV (unmanned aerial vehicle) activity, and persistent air raid sirens adversely affect the somatic and mental health of the younger generation. Notably, the clinical presentation and progression of diseases acquire specific characteristics when there are pre-existing chronic conditions within the somatic (specifically endocrine) system. The study included 314 patients with type 1 diabetes mellitus (DM1) and a disease duration of at least one year, who underwent examination and treatment at the clinic of the SI "Institute for Children and Adolescents Health Care of the NAMS of Ukraine" before and after the onset of the war in Ukraine. It was established that under wartime conditions, adolescents with DM1 frequently develop psychological and pathopsychological symptom complexes, as well as depressive and anxiety disorders. These findings are critical for the formulation of psychological and psycho therapeutic intervention and support programs. The development of mental disorders in adolescents with DM1 was influenced by both psychological trauma related to the war and factors associated with the clinical course of the disease, such as: the pain characteristics of the illness, the internal representation of the disease, polypharmacy, the quality of medico-psychological support, and the socio-environmental milieu. Acute and chronic stress caused by warfare and military operations impairs the adaptive capacities of adolescents with DM1. The development of specialized programs for the differentiated therapy of emotional and stress-related disorders in adolescents must be based on the forecasting and planning of medical-therapeutic interventions, with a fundamental focus on identifying "targets for therapeutic intervention" to ensure the effective application of medico-psychotherapeutic method.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2026 Issue 1, 180, 499-513 pages, index UDC 616.89-008-053.6-(1-07):616.379-008.64

DOI:

10.29254/2077-4214-2026-1-180-499-513