Nikitin О. D., Pasechnikov S. P., Golovko S. V., Hrytsai V. S., Samchuk P. O., Yasynetskyi M. O.

EVALUATION OF SEXUAL AND REPRODUCTIVE FUNCTION IN PATIENTS WITH CHRONIC PROSTATITIS/CHRONIC PELVIC PAIN SYNDROME

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About the author:

Nikitin О. D., Pasechnikov S. P., Golovko S. V., Hrytsai V. S., Samchuk P. O., Yasynetskyi M. O.

Heading:

CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

Annotation:

In recent years, researchers have paid considerable attention to the study of chronic pelvic pain syndrome and its impact on male infertility. Although the exact mechanisms of this relationship are not yet fully understood, it is known that CPPS negatively affects sperm counts. Possible causes include inflammatory processes in the male genitalia, metabolic syndrome, chronic inflammatory bowel disease, human papillomavirus (HPV) infection, and autoimmune disorders. The authors of the article evaluated the quality of life and spermogram results before treatment and after 6 months of therapy in 42 patients diagnosed with chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS). The combination therapy included drugs based on L-arginine, L-glutamine, L-carnitine, Vitamins C and E, and Serenoa repens extract. The results of the study show that in the group of patients, oligozoospermia of various degrees was observed with a high degree of confidence before treatment. After 6 months of treatment, normozoospermia was observed, and patients experienced significant pain relief, as well as a significant improvement in erectile and reproductive function. The proportion of patients with severe dysfunction decreased from 28.6% to 7.1%. Improvement in the SHIM score correlates with an overall reduction in pain and improved quality of life, which other instruments, including the NIH-CPSI, have also noted.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 4, 175, 441-450 pages, index UDC 616.65-002.2-06.616.697

DOI:

10.29254/2077-4214-2024-4-175-441-450