Marchenko O. H., Bodnar V. A., Pryimenko N. O., Stetsenko O. O., Miahkokhlib A. A., Olefir S. A., Svyrydenko N. P.

CURRENT CLINICAL AND EPIDEMIOLOGICAL FEATURES OF MEASLES: A RETROSPECTIVE COHORT STUDY COMPARING THE 2006 AND 2018 OUTBREAKS

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Marchenko O. H., Bodnar V. A., Pryimenko N. O., Stetsenko O. O., Miahkokhlib A. A., Olefir S. A., Svyrydenko N. P.

Heading:

CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

Annotation:

The article is dedicated to defining the clinical and epidemiological features of the current course of measles when comparing the outbreaks of the disease between 2006 and 2018. The medical records of 218 patients who were in hospital in a communal enterprise of the Poltava Regional Clinical Infectious Diseases Hospital of the Poltava Regional Council with the diagnosis "Measles" for the periods of epidemic outbreaks of measles epidemic outbreaks between January and May 2006 and between January and December 2018. The analysis showed that in general, among both groups, persons of young age from 18 to 39 years prevailed, however, during the outbreak of 2018, the age structure of patients was registered in more patients older than 30 years than during the outbreak of 2006. According to gender analysis, men were significantly more prevalent among those hospitalized during the 2018 outbreak when compared to data from 2006. A comparative analysis of the clinical course of the disease depending on the year of the epidemic outbreak showed that among those hospitalized in 2018, such clinical symptoms as general weakness, runny nose, enlargement of local lymph nodes, conjunctivitis and Koplik spots were less likely to be diagnosed, but manifestations of intestinal syndrome were more often recorded than during the outbreak in 2006. The findings suggest some changes in the clinical course of measles and the frequent absence of measles-specific features during the last large-scale outbreak. This complicates the diagnosis of measles and requires increased awareness from doctors about this disease.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 1, 172, 189-194 pages, index UDC 616.915-036.22‘’2006:2018’’-047.44

DOI:

10.29254/2077-4214-2024-1-172-189-194