Sultanova M. M., Hasanova R. M.
ASSESSMENT OF VISUAL FUNCTIONS OF CHILDREN BORN IN CONSANGUINEOUS MARRIAGE ON THE BASIS OF APPEAL TO THE DISABILITY COMMISSION
Show/Download
About the author:
Sultanova M. M., Hasanova R. M.
Heading:
PEDIATRICS
Type of article:
Scientific article
Annotation:
The records of 560 patients aged 1-15 years were analyzed. Anamnesis was collected, routine studies were conducted. 2 groups were identified: 1 – children born in consanguineous marriage (409 patients), 2 – from non-related parents (151 people). Light perception, visual acuity, peripheral vision, and binocular vision were evaluated. In boys of group 1, visual acuity of the right eye corresponded to the norm in 5 cases, and of the left eye in 7 observations. Poor eyesight was observed in 182 cases in the right eye, in 183 – in the left. Blindness was registered in 75 boys in the right eye, 72 in the left. In patients of group 2, normal vision was recorded in 15 patients in the right eye, in 12 in the left. Poor eyesight was detected in 59 boys in the right eye, 60 in the left. Blindness was recorded in 16 cases on the right gas, in 18 on the left. Impaired light perception was detected in 132 observations (124 patients of group 1, 8 from the second group). Violation of perimetry was diagnosed in 127 patients (10 patients from group 2). Binocular vision impairment was observed in 482 children (124 out of 2 groups). Patients born in consanguineous marriage have significant violations of all visual functions of the eye. Pathology manifests itself earlier and proceeds more severely in comparison with patients born to unrelated parents. Genetically determined pathology of the visual organ leads to early disability of patients from families confined between close relatives.
Tags:
Bibliography:
- Kavitha V, Gangrade AK, Heralgi MM, Haragoppa S. Ocular abnormalities in children with developmental delay. Indian J Ophthalmol. 2023;71(10):3328- 3334. DOI: 10.4103/IJO.IJO_3358_22.
- Miao N, Zhang Y, Liao JY, Zhou L, He JC, Yang RQ, et al. Novel homozygous ADAMTS17 missense variant in Weill-Marchesani syndrome. Int J Ophthalmol. 2023;16(5):694-699. DOI: 10.18240/ijo.2023.05.04.
- Alkatan HM, Bedaiwi KM, Al-Faky YH, Maktabi AMY. Demographics and histopathological characteristics of enucleated microphthalmic globes. Sci Rep. 2022;12(1):5283. DOI: 10.1038/s41598-022-09261-2.
- Pedersen KB, Kappelgaard P, Kessel L, Sandfeld L, Zibrandtsen N, Bach-Holm D. Primary congenital glaucoma in Denmark, 1977-2016. Acta Ophthalmol. 2020;98(2):182-189. DOI: 10.1111/aos.14207.
- Pandova MG, Abduljalil T, Elshafey AE, Abdelmoaty SMA, Albastawisy HI, Bastaki LA, et al. Inherited retinal dystrophies in a Kuwaiti tribe. Ophthalmic Genet. 2022;43(4):438-445. DOI: 10.1080/13816810.2022.2045509.
- Oncel Acır N, Taskiran Kandeger B. Early diagnosis for cerebrotendinous xanthomatosis with juvenile cataract and family history. Ophthalmic Genet. 2023;44(4):361-365. DOI: 10.1080/13816810.2023.2197492.
- AlAbdi L, Alshammari M, Helaby R, Khan AO, Alkuraya FS. PMEL is mutated in oculocutaneous albinism. Hum Genet. 2023;142(1):139-144. DOI: 10.1007/s00439-022-02489-y.
- Yahalom C, Braun R, Patal R, Saadeh I, Blumenfeld A, Macarov M, et al. Childhood visual impairment and blindness: 5-year data from a tertiary low vision center in Israel. Eye (Lond). 2022;36(10):2052-2056. DOI: 10.1038/s41433-021-01743-3.
- Salmon JF. Kanski‘s Clinical Ophthalmology: A Systematic Approach. 10th ed. Elsevier; 2024. 968 p.
Publication of the article:
«Bulletin of problems biology and medicine», 2024 Issue 4, 175, 611-619 pages, index UDC 616.831-009.11-053.3+616-036.865