Riabukha O. I.

TO THE CHARACTERIZATION OF MORPHOLOGICAL AND FUNCTIONAL FEATURES OF OF FOLLICULAR THYROCYTES UNDER CONDITIONS OF ALIMENTARY IODINE DEFICIENCY

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About the author:

Riabukha O. I.

Heading:

PROSPECTS FOR THE DEVELOPMENT OF MORPHOLOGICAL AND CLINICAL RESEARCH

Type of article:

Scientific article

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Peculiarities of relationships between the components of the morphofunctional capability’s profile of follicular thyrocytes were studied using the Pearson correlation analysis method. The study was performed on the thyroid glands of male albino rats under normal conditions and on an iodine-deficient diet. The method of electron microscopy and a set of author’s methods are applied - determination of special capabilities’ profiles of hormonepoietic cells, semi-quantitative analysis of electronograms, tabular versions of correlation portraits. Analyzing the correlation portraits deepened the knowledge about the interrelationships and interdependencies between the components of the follicular thyrocyte. Under the conditions of sufficient iodine supply, the connections of the convoluted, unchanged lateral membranes of thyrocytes and oval-shaped nuclei, the chromatin of which is fine-grained, and the marginal layer is compact, are of the greatest functional importance, while with dietary iodine deficiency, the main mechanisms of cell adaptation to activity under unfavorable conditions are connections bundles of cubic and prismatic cells, the nuclear chromatin of which is fine-grained and sparse, and the marginal layer is fragmented narrow or wide.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 2, 173, addition, 46-48 pages, index UDC 616.441-008.64:546.15]-018.7-008.1

DOI:

10.29254/2523-4110-2024-2-173/addition-46-48