Rozhnov A. S., Astapenko O. O., Narazhaiko L. F., Denysenko V. D.

STUDY OF THE CYTOTOXICITY OF BIODEGRADABLE POLYURETHANE MEMBRANES FOR GUIDED BONE REGENERATION IN THE MAXILLOFACIAL REGION

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About the author:

Rozhnov A. S., Astapenko O. O., Narazhaiko L. F., Denysenko V. D.

Heading:

MODERN ACHIEVEMENTS OF DENTISTRY

Type of article:

Scientific article

Annotation:

The aim of this study was to evaluate the cytotoxicity of experimental samples of polyurethane membranes intended for use in guided bone regeneration in the maxillofacial region. The biocompatibility of the materials was assessed using a fibroblast cell culture method involving direct contact between the polymer surface and cellular elements under standard in vitro conditions. The tested membranes did not cause any changes in fibroblast growth dynamics, morphology, or migration compared to the control group. The results indicate high biocompatibility of the experimental polyurethane membranes and support their potential as promising materials for application in maxillofacial surgery.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2025 Issue 4, 179, addition, 152-155 pages, index UDC 678.664

DOI:

10.29254/2523-4110-2025-4-179/addition-152-155