Donchenko S. V., Bilash S. M.
STRUCTURAL ORGANIZATION OF THE ADRENAL GLANDS MEDULLA OF RATS IN NORMAL AND AFTER INFLUENCE OF FOOD ADDITIVE COMPLEX
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About the author:
Donchenko S. V., Bilash S. M.
Heading:
MORPHOLOGY
Type of article:
Scientific article
Annotation:
Taste plays a significant role in the life of every person. Our taste buds are responsible for recognizing flavors, determining the suitability of foods, protecting against harmful substances, and regulating food intake. A person always gets pleasure from tasty food, and sweet dishes cause positive emotions. Unfortunately, we consume food that contains many food additives and preservatives daily, although we know that it can be harmful. Tasty but not healthy food has become extremely common and available, and it is difficult for us to resist the temptation to eat it. Many nutritional supplements have been created to meet the needs of the food industry, as mass production of products is different from home cooking. These additives are necessary to preserve the product's appearance but should not harm buyers' health or mislead them. Today, there are many food additives that consumers are unaware of but which can affect human organs, particularly the adrenal glands. Some of the most common food additives we study include monosodium glutamate (E621), sodium nitrite (E250) and Ponceau 4R (E124). Consuming large amounts of dietary supplements can have the following effects: chest and abdominal pain, migraines, nausea, rapid heart rate (tachycardia), obesity, weakness, and allergic reactions. Particular attention should be paid to the effect of these supplements on the adrenal glands, as they can disrupt the function of these organs and contribute to the development of oncological diseases. Research on the morphology of the adrenal glands has been ongoing for many years. In recent decades, there has been an increase in the pathology of the adrenal glands as the negative influence of external and internal factors increases, which leads to disturbances in the structure and functioning of the glands. Adrenal glands play an essential role not only in the hypothalamic-pituitary-adrenal system but also in the endocrine system. Interest in changes in the structure of the adrenal glands does not fade among experimental medicine and scientists. Thanks to the improvement of computer diagnostic methods, the detection of both hormonally active and inactive, benign and malignant neoplasms of the adrenal glands is increasing. The most common endocrine disorders are hyperaldosteronism, adrenergic and estrogenic balance disorders. Computed tomography significantly improves the detection of tumors of various origins in the adrenal glands. Diagnosis and treatment of diseases of the adrenal glands is an urgent medical and social problem.
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Bibliography:
- Pronina OM, Koptev MM, Bilash SM, Yeroshenko GA. Response of hemomicrocirculatory bed of internal organs on various external factors exposure based on the morphological research data. World of medicine and biology. 2018;1(63):153-7.
- Butnariu M, Sarac I. What is sodium glutamate and what effects it has on health. Journal of Applied Biotechnology and Bioengineering. 2019;6(5):223-6.
- Millan S, Satish L, Bera K, Sahoo H. Binding and inhibitory effect of the food colorants Sunset Yellow and Ponceau 4R on amyloid fibrillation of lysozyme. New Journal of Chemistry. 2019;9:3956-68.
- Wojciech P, Michael HR. A Text and Atlas: With Correlated Cell and Molecular Biology. 8th ed. USA: Wolters Kluwer Health Inc.; 2020. 606 p.
- Bilash SM, Donchenko SV, Pronina OM, Koptev MM, Oliinichenko YO, Onipko VV, et al. Morphometric features of the elements of the hemomicrocirculatory bed in the cortex of the adrenal glands influenced by the food additives complex. Wiadomosci Lekarskie. 2022 Jan;75(6):1558-1563.
- Pronina OM, Bilash SM, Kobeniak MM, Koptev MM, Pirog-Zakaznikova AV, Onipko VV, et al. Morphometric features of the structural components of the hemomicrocirculatory bed in the perivulnar region of the caecum in wound defect sutured with polyfilament suture material. Wiadomości Lekarskie. 2021 Jan;74(6):1382-1388.
- Bilash SM, Donchenko SV. Morfofunktsionalnyi stan nadnyrnykiv pry dii kompleksu kharchovykh dobavok (ohlyad literatury). Visnyk problem biolohii i medytsyny. 2020;3(157):13-19. [in Ukrainian]
- Yachmin AI, Kononov BS, Yeroshenko GA, Bilash SM, Bilash VP. A measure of the effect of complex food additives on rats’ adaptive responses. World of Medicine and Biology. 2020;1(71):232-235.
- Kononov BS. Strukturna orhanizatsiya mozochku laboratornykh tvaryn v normi ta u porivnyalʹno-vydovomu aspekti. Vísnik problem bíologii i meditsiny. 2020;4(158):272-276. [in Ukrainian].
- Oliynichenko YAO, Bilash SM, Pronina OM, Koptev MM, Oliynichenko MO, Bezeha OV, et al. Vplyv kompleksu kharchovykh dobavok na protsesy remodulyuvannya strukturnykh komponentiv tonkoho kyshechnyka, yak vazhlyva medyko-sotsialʹna problema suchasnoho stanu zabezpechennya hromadsʹkoho zdorovʺya naselennya Ukrayiny. Visnyk problem biolohiyi i medytsyny. 2021;3(161):65-70. [in Ukrainian].
- Bilash SM, Kononov BS, Pronina OM, Kononova MM, Bilash VP, Shostya AM, et al. Particularities associated with the expression of glial acidic fibrillary protein on the structural components of cerebellum of the rats influenced by the food additives complex. Wiadomości Lekarskie. 2021 June;74(6):1409-1413.
- Donchenko SV, Bilash SM. Structural organization of rats adrenal glands in normal state. Visnyk problem biolohiyi i medytsyny. 2022;4(167):291-295.
- Kostenko VO, Tsebrzhins’kii OI. Production of superoxide anion radical and nitric oxide in renal tissues sutured with different surgical suture material. Fiziolohichnyi zhurnal. 2000;46(5):56-62.
- Chekalina NI. Resveratrol has a positive effect on parameters of central hemodynamics and myocardial ischemia in patients with stable coronary heart disease. Wiadomosci lekarskie. 2017;70(2):286-291.
Publication of the article:
«Bulletin of problems biology and medicine», 2023 Issue 2, 169, 381-386 pages, index UDC 611.452-024:613.29
