Gasimov N. A., Mammadov N. I., Akberova I. K., Hajiyeva A. E.

QUALITY OF LIFE AND LONG-TERM RESULTS OF PATIENTS OPERATED ON FOR COMPLICATED PEPTIC ULCER OF THE STOMACH AND DUODENUM USING MINIMALLY INVASIVE TECHNOLOGIES

---

Show/Download

About the author:

Gasimov N. A., Mammadov N. I., Akberova I. K., Hajiyeva A. E.

Heading:

CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

Annotation:

The long-term treatment results and quality of life of 163 patients out of 261 patients with complicated gastric and duodenal ulcer were analyzed. Complications with bleeding of gastric ulcer and duodenal ulcer were in 55 (33.7%), with perforation in 108 (66.3%) patients. In the control group, traditional, "open" surgical interventions were performed in 164 (62.8%) patients, and minimally invasive endovideosurgical operations were performed in 97 (37.2%) cases. Of the 186 patients, 124 (66.7%) underwent traditional suturing of a perforated gastroduodenal ulcer during laparotomy, and 62 (33.3%) underwent minimally invasive endosurgical surgical interventions. A comparison of long-term treatment results showed that simple ulcer suturing followed by anti-ulcer therapy gives relapses in 8.1% of cases and requires repeated surgical interventions in 4.8% of cases. After performing vagotomy with gastric drainage surgery, post-vagotomy disorders were diagnosed in 20.0% of cases. A comparison of long-term Visik results showed that after combined suturing of a perforated gastroduodenal ulcer, excellent (80.0%) and good (6.9%) results prevail. In the group of patients who underwent laparoscopic suturing of a perforated gastroduodenal ulcer, excellent (86.7%) and good (10.0%) results prevailed. All indicators of quality of life were similar in patients of the main and control groups. After minimally invasive endosurgical operations in patients with ulcerative duodenal bleeding, excellent results were obtained in 92.0% of the patient, good results in 4.0%. At the same time, in patients with duodenal ulcer complicated by gastroduodenal bleeding, after traditional, "open" surgical interventions, excellent results were obtained in 83.3% of patients, good results in 6.7%. A significant decrease in the quality of life in patients of the control group was associated with laparotomy. Thus, the use of minimally invasive laparoscopic methods is characterized by an adequate and prolonged decrease in gastric acid production, are not associated with an increase in the frequency of prostagotomy syndromes, and are accompanied by good and excellent results in most of the operated patients, compared with traditional, "open" surgical interventions.

Tags:

Bibliography:

1. Tarasenko SV, Natalsky AA, Panin SI, Sazhin IV, Yudin VA, Sazhin VP, et al. Modern aspects of the complex treatment of perforated gastric and duodenal ulcer. Khirurgiya. Zurnal im. N.I. Pirogova. 2021;1:42-46. DOI: https://doi.org/10.17116/hirurgia202101142.
2. Peiffer S, Pelton M, Keeney L, Kwon EG, Ofosu-Okromah R, Acharya Y, et al. Risk factors of perioperative mortality from complicated peptic ulcer disease in Africa: Systematic review and meta-analysis. BMJ Open Gastroenterol. 2020;7(1):1-12. DOI: https://doi.org/10.1136/bmjgast-2019-000350.
3. Sоreide K, Thorsen K, S0reide JA. Strategies to improve the outcome of emergency surgery for perforated peptic ulcer. Br J Surg. 2014;101(1):e51-64. DOI: 10.1002/bjs.9368.
4. Berkinov OB, Khakimov MS, Matkuliyev UI, Ashurov SHE, Karimov MR, Beknazarov IR, et al. Some aspects of diagnosis and treatment of perforated duodenal ulcers. Bulletin of Emergency Medicine. 2018;11(4):26-32.
5. Vachev AN, Koryttsev VK, Antropov IV, Shcherbatenko VYu. Why should we abandon the operation of simple closure for duodenal ulcer complicated by perforation? Vestnik khirurgii im. I.I. Grekova. 2018;3:41-44. DOI: https://doi.org/10.24884/0042-4625-2018-177-3-41-44.
6. Sazhin AV, Ivakhov GB, Stradymov EA, Petukhov VA. Surgical treatment of perforated peptic ulcers complicated by diffuse peritonitis: laparotomy or laparoscopy? (Part 1) Endoskopicheskaya khirurgiya. 2019;25(3):51-58. DOI: https://doi.org/10.17116/endoskop20192503151.
7. Gulov MK. The study of the quality of life of patients is an important tool to evaluate the effectiveness of surgical treatment of complicated peptic ulcer disease. Avicenna Bulletin. 2018;20(2-3):181-189.
8. Terekhina AA, Sergeeva YuS, Demchenko DYu. Subjective estimation of quality of life of patients after different types of operations on perforative gastroduodenal ulcer. Alleya nauki. 2017;5(16):229-235.
9. Trukhalev VA, Kukosh MV, Gomozov GI. Quality of life of patients after suturing the perforated ulcer. Meditsinkij almanakh. 2013;6(30):204- 208.
10. Panin SI, Beburishvili AG, Prudkov MI, Sovtsov SA, Timerbulatov VM, Bykov AV, et al. Open and laparoscopic surgery via minimally invasive approach in the treatment of perforated ulcer: a systematic review and metaanalysis. Khirurgiya. Zurnal im. N.I. Pirogova. 2021;(2):94-100. DOI: https://doi.org/10.17116/hirurgia202102194.
11. Khisamutdinova RI, Timerbulatov ShV, Sagitov RB. Videolaparoscopic operations for perforated gastroduodenal ulcers. Practicheskaya onkologiya. 2017;6(107):127-130.
12. Isagawa Y, Igarashi M, Miyakuni T, Matsuno Y, Hagiwara K, So K, et al. Useful Method of Hand-Assisted Laparoscopic Surgery for Perforated Duodenal Ulcer: A Case Report. Journal of Nihon University Medical Association. 2017;76(6):301-304.
13. Visick AH. Conservative treatment of acute perforated peptic ulcer. Br Med J. 1946;2(4485):941-944.
14. Jenkinson C, Coulter A, Wright L. Short form 36 (SF-36) health survey questionnaire: normative data for adults of working age. BMJ. 1993;306(6890):1437-1440.

Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 4, 175, 316-326 pages, index UDC 616.62-003.7-056.4; 616.33 – 022.44 – 005.1. – 053.1: 616.342 – 002.44 – 08: 616.381 – 072.1

DOI:

10.29254/2077-4214-2024-4-175-316-326