Kosharniy V. V., Abdul – Ogly L. V., Kushnaryova K. A., Kozlovska G. O.

PECULIARITIES OF BLOOD SUPPLY AND STRUCTURE OF THE SMALL INTESTINE AND ITS ROLE IN BLAST INJURY

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About the author:

Kosharniy V. V., Abdul – Ogly L. V., Kushnaryova K. A., Kozlovska G. O.

Heading:

MORPHOLOGY

Type of article:

Scientific article

Annotation:

Blast-induced injuries of the abdominal cavity are characterized by high vulnerability of hollow and parenchymal structures, which is confirmed by numerous clinical and experimental observations. Primary and secondary intestinal perforations are of particular danger, the frequency of which varies depending on the conditions of exposure to the blast wave. At the same time, injuries to parenchymal organs are recorded in approximately one third of cases of abdominal blast trauma. Despite the sufficient amount of clinical data on the diagnosis and treatment of such injuries, the issues of pathogenesis and morphological changes in the early and delayed periods after barotrauma remain relevant. The aim of the study was to assess the influence of the acute period of barotrauma on the histomorphometric characteristics of the small intestine of white rats. The experiment was conducted on 20 animals, divided into control and experimental groups, for which abdominal barotrauma was simulated under anesthesia. Histological studies of the proximal small intestine were performed according to standard methods with subsequent morphometric analysis. Statistical processing of the results was carried out using the Student's t-test. The results of the work allow us to clarify the features of early structural changes in the small intestine after blast-induced barotrauma and may be useful for further study of the pathogenesis, diagnosis and possible approaches to the correction of such injuries.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2025 Issue 4, 179, 317-325 pages, index UDC 612.84:616-001.31-007.23 -092.9:534.222.2

DOI:

10.29254/2077-4214-2025-4-179-317-325