Zavgorodniy S. M., Gatia M. S., Kubrak M. A., Danyliuk M. B.

PARAMETERS OF INTRATHYROID HEMODYNAMICS IN PATIENTS WITH NODULAR TOXIC GOITER

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About the author:

Zavgorodniy S. M., Gatia M. S., Kubrak M. A., Danyliuk M. B.

Heading:

CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

Annotation:

The leading place in the structure of thyrotoxicosis in the world and Ukraine is occupied by toxic nodular goiter (TNG). The study aims to analyse intrathyroid hemodynamics results in the modes of color and energy Doppler mapping and pulse Doppler in patients with nodular toxic goiter. The study included 35 (100%) patients with nodular toxic goiter who were examined and subsequently operated on at the surgical department of the "VIZUS" Medical Center. All patients underwent ultrasound diagnostics to determine vascularization and intrathyroidal hemodynamics by means of Doppler mapping and pulsed dopplerometry. In patients with TNG, perinodular and mixed types of vascularization according to the scale of Rago T. prevailed (32 (91.4%) patients) and normal or small increase in the intensity of blood flow in the parenchyma of the thyroid gland (15 (75.0%) patients). In 29 (82.9%) examined, an increase in the peak systolic blood flow velocity in the upper thyroid artery (34.2 (19.4; 41.2) cm/s) was noted, in 24 (68.6%) an increase in the maximum diastolic blood flow velocity (16.2 (9.8; 20.8) cm/s), the maximum volumetric blood flow velocity was increased in 27 (77.1%) patients (1.4 (0.8; 1.6) ml/s), the resistance index - in 11 (31.4%) examined up to 0.9 (0.6; 1.1). In patients with TNG, according to the results of Doppler examination, perinodular and mixed types of vascularization with normal or slightly increased blood flow in the parenchyma of the thyroid gland were found in most cases. At the same time, in patients with a nodular lesion of one lobe of the thyroid gland, no significant difference was found in the intensity of intrathyroidal blood flow and quantitative parameters of blood flow in the affected and contralateral (healthy) lobes.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2023 Issue 3, 170, 210-217 pages, index UDC 6165.441-008.61-074/-076

DOI:

10.29254/2077-4214-2023-3-170-210-217