Bezkorovayna I. M., Sherstyuk O. O., Svintsytska N. L.
NASOLACRIMAL OBSTRUCTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS: A CLINICAL ANALYSIS
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About the author:
Bezkorovayna I. M., Sherstyuk O. O., Svintsytska N. L.
Heading:
CLINICAL AND EXPERIMENTAL MEDICINE
Type of article:
Scientific article
Annotation:
Pathology of the lacrimal system accounts for a significant proportion of ocular diseases and is of great medical and social importance. It is known that there is a stable correlation between the development of nasolacrimal duct obstruction (NLDO) and pathology of the eye surface and eyelids (conjunctivitis, keratoconjunctivitis, dry eye syndrome). Additionally, a strong association has been observed with systemic diseases, including diabetes mellitus (DM). The higher prevalence of NLDO in patients with type 2 diabetes mellitus (T2DM) is associated with the specific characteristics of inflammatory processes and immune response dysfunctions. The clinical specifics of NLDO in T2DM remain insufficiently studied. This study included two groups of patients: the main group consisted of 40 patients with T2DM, while the control group comprised 40 patients without DM. Standard ophthalmologic examinations were performed, along with specific tests to diagnose NLDO. The results were analyzed considering the level of DM compensation, age, gender, and the frequency of NLDO development at different levels. In cases of decompensated diabetes, the frequency of NLDO was 1.4 times higher than in subcompensated cases and 2.2 times higher than in compensated cases. The presence of T2DM significantly increases the risk of lacrimal system pathology: NLDO was 2.6 times higher, and bilateral NLDO was 2.5 times higher compared to individuals without DM. In women with T2DM, NLDO was 1.5 times more common than in men. The presence of T2DM also leads to the development of NLDO at a younger age: the average age of affected patients was 6.8 years younger compared to patients without diabetes.
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Publication of the article:
«Bulletin of problems biology and medicine», 2024 Issue 4, 175, 265-274 pages, index UDC 616.379-008.64:616.214:617.764.1
