Mirzazade V. A., Aliyeva A. Z., Sultanova S. S., Guseynova N. N.

FASTING GLUCOSE AND GLUCOSE TOLERANCE TEST INDEXES IN SCREENING OF DIABETES AND PREDIABETES

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About the author:

Mirzazade V. A., Aliyeva A. Z., Sultanova S. S., Guseynova N. N.

Heading:

CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

Annotation:

The presented article provides information about the research work conducted to study new indicators for screening diabetes and prediabetes and the interaction between them. 182 people were involved in the study and were randomly divided into 2 equal groups: the training group (91 people; 23 men, 68 women) and the control group (91 people; 23 men, 68 women). From laboratory tests, fasting glucose, glycohemoglobin were determined, and a 2-hour oral glucose tolerance test (with a 75 g glucose load) was performed. Based on the anamnestic and anthropometric data of 182 people, as well as laboratory test results, a questionnaire was created for the early detection of diabetes and prediabetes. In the preparation of the questionnaire, 288 signs were analyzed for each person and indices were calculated using the multiple linear regression method. The most informative indicators were age, waist circumference, body mass index, systolic and diastolic blood pressure, history of arterial hypertension, history of gestational diabetes, physical activity level, and frequency of diabetes in first-degree relatives. Using simple indicators in the new questionnaire, each person can obtain estimated results that are very close to the real laboratory test results without undergoing laboratory tests. A statistically significant correlation between the real results obtained in the laboratory test and the indices was achieved in both groups (training group; p<0.001) (control group; p<0.001). The use of cut-off points made it possible to detect 100% of patients with diabetes, 67% of prediabetes, and 83-85% of people with normal carbohydrate metabolism.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2025 Issue 1, 176, 244-251 pages, index UDC 616.43

DOI:

10.29254/2077-4214-2025-1-176-244-251