PHOTODYNAMIC THERAPY IN THE COMPREHENSIVE TREATMENT OF ENDOPERIODONTAL LESIONS

Nikolishin A. K., Kotelevska N. V., Kostyrenko O. P., Bubliy T. D., Ivanytskyi I. O., Sidash Yu. V.

PHOTODYNAMIC THERAPY IN THE COMPREHENSIVE TREATMENT OF ENDOPERIODONTAL LESIONS


Show/Download

About the author:

Nikolishin A. K., Kotelevska N. V., Kostyrenko O. P., Bubliy T. D., Ivanytskyi I. O., Sidash Yu. V.

Heading:

MODERN ACHIEVEMENTS OF DENTISTRY

Type of article:

Scientific article

Annotation:

Endoperiodontal lesions (EPL) are a complex clinical problem of modern therapeutic dentistry, as they combine pathological changes in the pulp and periodontal tissues, which mutually aggravate the course of inflammation. Their etiopathogenesis is due to infectious, immune, traumatic and occlusive factors, which lead to the spread of the inflammatory process through the dentinal tubules, additional root canals or apical foramen. But the primary one is microbial contamination, which leads to an inflammatory reaction and, as a result, to damage to the pulp and periodontal tissues. Also, endodontic and periodontal diseases can develop independently in one tooth and be combined during their long-term course. Microorganisms play a major role in the development of endoperiolesions. Moreover, microbiological studies show the same microbiota in the root canals and periodontal pockets of the affected tooth. Traditional methods of therapy – instrumental and drug treatment of root canals, antiseptic and anti-inflammatory therapy – often prove to be insufficiently effective in the presence of a pronounced inflammatory or purulent process. This necessitates the improvement of conservative approaches.

Tags:

disinfection, endoperiodontal lesions, photodynamic therapy, photosensitizer, root canals

Bibliography:

  1. Petrushanko TO, Popovych IYu, Moshel TM. Otsinka dii khvorobotvornykh faktoriv u patsiientiv iz heneralizovanym parodontytom. Klinichna stomatolohiia. 2020;2:24-32. [in Ukrainian].
  2. Sidash YuV, Kostyrenko OP. Morfolohichne obhruntuvannia efektyvnosti fotodynamichnoi terapii u patsiientiv iz khronichnym heneralizovanym parodontytom na tli hipertonichnoi khvoroby. Visnyk problem biolohii i medytsyny. 2021;161:332-336. DOI: 10.29254/2077-4214-2021-3-161-332-336. [in Ukrainian].
  3. Ricucci D, Loghin S, Siqueira JF Jr. Exuberant Biofilm infection in a lateral canal as the cause of short-term endodontic treatment failure: report of a case. J Endod. 2013;39(5):712-8. DOI: 10.1016/j.joen.2012.12.008.
  4. Nikolishyn AK, Popovych IYu, Bublii TD, Sidash YuV, Kotelevska NV, Heranin SI. Innovatsiini tekhnolohii v praktyku endodonchii. Poltava: TOV NVP “Ukrpromtorhservis”; 2021. 112 s. [in Ukrainian].
  5. Sidash YuV, Kostyrenko OP, Petrushanko VM. Eksperymentalne doslidzhennia furkatsiinoi dilianky y perspektyvy yii kompleksnoho likuvannia. Ukrainskyi stomatolohichnyi almanakh. 2021;2:49-53. [in Ukrainian].
  6. Kwiatkowski S, Knap B, Przystupski D, Saczko J, Kędzierska E, Knap-Czop K, et al. Photodynamic therapy - mechanisms, photosensitizers and combinations. Biomed Pharmacother. 2018;106:1098-1107. DOI: 10.1016/j.biopha.2018.07.049.
  7. Marasini S, Leanse LG, Dai T. Can microorganisms develop resistance against light based anti-infective agents? Adv Drug Deliv Rev. 2021;175:113822. DOI: 10.1016/j.addr.2021.05.032. Erratum in: Adv Drug Deliv Rev. 2023;199:114971. DOI: 10.1016/j.addr.2023.114971.
  8. Nunes LP, Nunes GP, Ferrisse TM, Strazzi-Sahyon HB, Cintra LTÂ, Dos Santos PH, et al. Antimicrobial photodynamic therapy in endodontic reintervention: A systematic review and meta-analysis. Photodiagnosis Photodyn Ther. 2022;39:103014. DOI: 10.1016/j.pdpdt.2022.103014.
  9. Bordea IR, Hanna R, Chiniforush N, Grădinaru E, Câmpian RS, Sîrbu A, et al. Evaluation of the outcome of various laser therapy applications in root canal disinfection: A systematic review. Photodiagnosis Photodyn Ther. 2020;29:101611. DOI: 10.1016/j.pdpdt.2019.101611.
  10. Vendramini Y, Salles A, Portella FF, Brew MC, Steier L, de Figueiredo JAP, et al. Antimicrobial effect of photodynamic therapy on intracanal biofilm: A systematic review of in vitro studies. Photodiagnosis Photodyn Ther. 2020;32:102025. DOI: 10.1016/j.pdpdt.2020.102025.

Publication of the article:

«Bulletin of problems biology and medicine», 2025 Issue 4, 179, addition, 148-151 pages, index UDC 616.314.17-085

DOI:

10.29254/2523-4110-2025-4-179/addition-148-151

Was this article helpful?

Leave a Reply

Your email address will not be published. Required fields are marked *


The reCAPTCHA verification period has expired. Please reload the page.