Kushnir Yu. A.

POSSIBILITIES OF USING THE SANS METHOD FOR ASSESSING THE FEATURES OF NEGATIVE SYMPTOMS IN PATIENTS WITH SCHIZOPHRENIA

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About the author:

Kushnir Yu. A.

Heading:

CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

Annotation:

The prevalence of schizophrenia in the world is from 0.4 to 1.4%, and the number of patients with negative disorders in this group reaches 90%. Negative symptoms are considered main components of schizophrenia. Negative symptoms are associated with negative social and economic consequences; therefore, their recognition, timely assessment and treatment are relevant. Modern investigations about negative symptoms in schizophrenia remain unsystematized and scattered, which requires further clarification and addition. The purpose of the study was to determine the characteristics of the clinical and psychopathological structure and the severity of negative symptoms in patients with schizophrenia in order to improve the diagnosis and treatment of negative symptoms in schizophrenia. 331 patients with schizophrenia were examined: 252 patients with negative symptoms of schizophrenia (main group) and 79 patients with positive symptoms of schizophrenia (control group). The research used a comprehensive approach, consisting in the use of clinical-psychopathological, psychometric (SANS scale) and statistical research methods. The features of the manifestations of affective flattening, alogia, abulia, apathy, anhedonia, asociality, and impaired attention in patients with negative and positive symptoms of schizophrenia were analyzed. Features of the clinical-psychopathological structure and severity of negative symptoms in patients with schizophrenia were established. Among patients with negative symptoms of schizophrenia, mainly moderate and severe disorders of the components of affective flattening, alogia, abulia and apathy, anhedonia and asociality, and attention were determined. The obtained data can be used as diagnostic criteria when conducting differential diagnosis and choosing treatment strategies for patients with schizophrenia.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2023 Issue 4, 171, 210-217 pages, index UDC 616.895.8:616-085:615.86-07

DOI:

10.29254/2077-4214-2023-4-171-210-217