RISK-ORIENTED APPROACHES TO OPTIMIZE THE VOLUME OF EXPERIMENTAL STUDIES PESTICIDES’ HYGIENE STANDARD IN SOIL (first message)

  2. 2023
  3. RISK-ORIENTED APPROACHES TO OPTIMIZE THE VOLUME OF EXPERIMENTAL STUDIES PESTICIDES’ HYGIENE STANDARD IN SOIL (first message)

Korshun M. M., Korshun O. M., Martіianova Yu. V.

RISK-ORIENTED APPROACHES TO OPTIMIZE THE VOLUME OF EXPERIMENTAL STUDIES PESTICIDES' HYGIENE STANDARD IN SOIL (first message)

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About the author:

Korshun M. M., Korshun O. M., Martіianova Yu. V.

Heading:

HYGIENE, ECOLOGY AND EPIDEMIOLOGY

Type of article:

Scientific article

Annotation:

Today, threshold concentrations are experimentally established for four indicators of harmfulness to justify the threshold limit value (TLVs) of active substances (a.s.) of pesticides. The goal is to justify risk-oriented approaches to assessing the danger of harmful inhalation effects on the human body of pesticides during their migration from the soil to the surface layer of atmospheric air to optimize the volume of experimental studies when justifying the hygienic standard in the soil. On an array of 82 a. s., for which TLVs have been established, mathematical modeling of soil-to-air migration has been carried out; the coefficient of the possibility of inhalation poisoning (CPIP), potential risk of occupational exposure (PROE) and potential risk of unprofessional influence (PRUPI) were calculated. The molar mass and fraction a. s. with a high bioaccumulative capacity among compounds of the new generation (starting from 1970) is higher than the old (up to and including 1969). According to saturated vapor pressure and Henry's constant, most a. s. is a little volatile. 24.0% and 7.3% were classified as extremely dangerous according to the acute inhalation toxicity and the hygienic standard's value in the working area's air. s., to dangerous – 49.3% and 75.6% a. s., the rest are moderately and slightly dangerous; no statistically significant differences between different generations were found. By CPIP 97.3% a. s. are not dangerous. Acceptable is a PROE of 90.2% a. s. and PRUPI 57.1% a. s.; the share of such a. s. significantly higher among compounds of the new generation. Evaporation from the soil into the atmospheric air of all studied a. s. will not lead to acute inhalation poisoning, in 90.2% of cases will not cause harmful inhalation effects on the body of agricultural workers and in 57.1% of cases, will not harm persons who do not have professional contact with pesticides.

Tags:

atmospheric air, inhalation exposure, maximum permissible concentration, pesticides, soil

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Publication of the article:

«Bulletin of problems biology and medicine», 2023 Issue 2, 169, 148-158 pages, index UDC 613:632.95:614.77

DOI:

10.29254/2077-4214-2023-2-169-148-158

2023 Issue 2, 169
atmospheric air inhalation exposure maximum permissible concentration pesticides soil
29.06.2023
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