Borysenko V. V.
PATHOMORPHOSIS OF CLINICAL FORMS OF SCHIZOPHRENIA UNDER CHANGING SOCIAL AND STRESS LOADS: A 26-YEAR ANALYSIS IN THE INPATIENT POPULATION OF POLTAVA REGION (1999–2024)
Show/Download
About the author:
Borysenko V. V.
Heading:
MODERN ACHIEVEMENTS OF MEDICINE
Type of article:
Scientific article
Annotation:
The article presents the results of a retrospective clinical and statistical analysis of the dynamics of schizophrenia incidence among inpatients in the Poltava region over a 26-year period (1999-2024). The aim of the study was to investigate the features of nosological and syndromological pathomorphosis of schizophrenia by analyzing the dynamics of clinical forms (F20.x) among hospitalized patients. It was found that the overall dynamics of hospitalizations follow a U-shaped trend, with the 2022-2024 period characterized by a sharp surge in the schizophrenia patient cohort (55.4% increase in F20 in 2022). Stable dominance of the Paranoid form (F20.0) was observed, along with a statistically significant V-shaped resurgence of the Hebephrenic form (F20.1) and a steady increase in the proportion of “Other forms” of schizophrenia (F20.8). Importantly, unlike international trends suggesting mitigation, the proportion of the Catatonic form (F20.2) remains stably low, at approximately ~0.3%. It is discussed that the stress of wartime acts as a powerful factor causing regressive pathomorphosis, marked by the reappearance of disorganized forms, which contradicts the expected overall mitigation of schizophrenia clinical subtypes.
Tags:
Bibliography:
- World Health Organization. The ICD-10 Classification of Mental and Behavioural Disorders: Clinical descriptions and diagnostic guidelines. Geneva: WHO; 1992. 377 p.
- Sartorius N. The trends in the development of psychiatry in the world. Psychiatria Danubina. 2019;31(5):605-7.
- Maruta NO, Panko TV, Kalenska HYu. Osoblyvosti klinichnoho patomorfozu shyzofrenii na suchasnomu. Ukrayinskyy visnyk psykhonevrolohiyi. 2018;26(1):38-42. [in Ukrainian].
- Frankova I. Mental health care in Ukraine during the war. Lancet Psychiatry. 2022;9(5):12-3.
- Napryienko OK. Psikhiatriya ta narkolohiya. 3-e vyd. Kyiv: Medytsyna; 2017. 540 s. [in Ukrainian].
- Pidkorytov VS, Revenok OA. Epidemiolohiya psykhichnykh rozladiv v Ukrayini v umovakh sotsialnoho stresu. Arkhiv psykhіatrії. 2023;29(1):5-12. [in Ukrainian].
- Yurieva LM. Shyzofreniya: klinika, diahnostyka, terapiya ta reabilitatsiya v svitli suchasnykh kontseptsiy. Kyiv: Sfera; 2016. 288 s. [in Ukrainian].
- Sharafati-Chaleshtori R, Sharafati-Chaleshtori N. Trends in the incidence of catatonic schizophrenia. Clin Psychopharmacol Neurosci. 2020;18(3):447-448.
- Chaban OS, Khaustova OO. Psykhichne zdorovya v umovakh viyny: vid vyzhyvannya do adaptatsiyi. Zhurnal Natsionalnoyi akademiyi medychnykh nauk Ukrayiny. 2022;28(2):12-20. [in Ukrainian].
Publication of the article:
«Bulletin of problems biology and medicine», 2025 Issue 4, 179, addition, 104-106 pages, index UDC 616.895.8-036.22(477.53):614.2
