Samoilenko I. A., Nekhanevych Zh. M., Yunkin Ya. O., Dorogina O. S., Gudaryan S. O.

CLINICAL ASPECTS OF THE USE OF DENTAL IMPLANTS IN PATIENTS WITH METABOLIC SYNDROME

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About the author:

Samoilenko I. A., Nekhanevych Zh. M., Yunkin Ya. O., Dorogina O. S., Gudaryan S. O.

Heading:

DENTISTRY

Type of article:

Scientific article

Annotation:

Metabolic syndrome (MS) (Reaven's syndrome) is a set of pathologically related metabolic disorders in a single patient. In addition to smoking, which is considered a decisive risk factor for vascular diseases (coronary heart disease), there are four other equally important factors: obesity, hypertension, lipid metabolism disorders accompanied by hypertriglyceridemia and decreased HDL levels, insulin resistance, or impaired glucose tolerance, the main cause of type 2 diabetes mellitus. However, such patients also require restoration of the dentition in cases of secondary edentulism through implant placement, the risks of integration of which are significantly reduced in these conditions. The aim of the study was to increase the clinical effectiveness of dental implantation in patients with metabolic syndrome through comprehensive preoperative preparation and the use of implants with an SLA-type surface. The study included 60 patients (aged 42 to 68 years) diagnosed with metabolic syndrome (MS), who had 90 intraosseous implants (Neobiotech, Straumann, Osstem) installed. Before the operation, medication was used to correct metabolic disorders, and antioxidant and vascular therapy was performed. Postoperative observation lasted 12 months. Implant survival was 94.6% in patients with MS, which was not statistically different from the control group (98.2%). The average marginal bone loss per year was 1.02±0.24 mm. A negative correlation was found between HbA1c levels and implant stability index (ISQ) – r= –0.62, p<0.05. Metabolic syndrome is not an absolute contraindication to dental implantation. Compensation for metabolic disorders, the use of implants with a modified SLA surface, and the application of objective methods for osseointegration control enable high clinical outcomes.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2025 Issue 4, 179, 433-439 pages, index UDC 616.314-089.843:616-008.9-008.6

DOI:

10.29254/2077-4214-2025-4-179-433-439