Zyukov O. L., Zinchenko N. I.
CHARACTERISTICS OF THE PREVALENCE OF RISK FACTORS FOR THYROID CANCER AMONG THE ADULT POPULATION AS A BASIS FOR THE DEVELOPMENT OF PREVENTIVE STRATEGIES
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About the author:
Zyukov O. L., Zinchenko N. I.
Heading:
SOCIAL MEDICINE, ECONOMY AND HEALTH CARE ORGANIZATION
Type of article:
Scientific article
Annotation:
The medical and social significance of thyroid diseases has increased significantly in recent decades. This trend is caused not only by the deterioration of the environment and the influence of harmful behavioral habits of society, but also by the progress of medicine in the field of diagnostics and treatment, especially in oncological diseases. Numerous studies indicate an increase in the incidence of thyroid cancer, however, mortality from this pathology remains stable. Thyroid oncopathology remains one of the few types of cancer, the prevalence of which is increas ing over time, despite advances in medicine. Over the past few years, it has been established that overdiagnosis is one of the factors of the stable growth of the incidence, and, most likely, we are observing a combination of both a systematic error in detection and a real increase in the number of cases of this nosology. In general, this problem manifests as a multifactorial phenomenon, influenced by the environment, metabolism, diet, and hormones, possibly interacting with genetic predisposition. Although most cases of thyroid cancer are curable, the burden on healthcare is significant, so the increase in the number of thyroid cancer cases in Ukraine and in the world as a whole is a strong argument in favor of studying this problem in order to contribute to improving the quality of life and reducing mor tality. To study the prevalence of risk factors for thyroid cancer among the adult population, the results of a question naire survey were evaluated, taking into account age- and gender-specific characteristics, as a basis for improving preventive measures and algorithms for early detection of thyroid nodular pathology.
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Bibliography:
- Ustinov O.V. Zdorovya shchytovydnoyi zalozy: informatsiya dlya likariv i patsiyentiv. Ukr. med. chasopys. 2020. Dostupno: https://umj.com. ua/uk/ novyna-178989-zdorov-ya-shhitovidnoyi-zalozi-informatsiya-dlya-likariv-i-patsiyentiv. [in Ukrainian].
- Street ME, Shulhai AM, Petraroli M, Patianna V, Donini V, Giudice A, et al. The impact of environmental factors and contaminants on thyroid function and disease from fetal to adult life: current evidence and future directions. Front Endocrinol (Lausanne). 2024;15:1429884. DOI: 10.3389/fendo.2024. 1429884.
- Tsentr hromadskoho zdorovia Ukrainy. Natsionalnyi portal stratehichnoi informatsii u sferi hromadskoho zdorovia. Kyiv: Derzhavna ustano va Tsentr hromadskoho zdorovia Ministerstva okhorony zdorovia Ukrainy; 2025. Dostupno: https://phc.org.ua/. [in Ukrainian].
- Tracy L. Overdiagnosis driving surge in thyroid cancer cases. Oncology Republic. Available from: https://www.oncologyrepublic.com.au/ over diagnosis-driving-surge-in-thyroid-cancer-cases/5776.
- Upravlinnya okhorony zdorovya Zhytomyrskoyi ODA. Bilshist zakhvoryuvan shchytopodibnoyi zalozy ye vylikovnymy. Zhytomyr: Upravlinnya; 2021. [in Ukrainian].
- Kitahara CM, Sosa JA. Understanding the ever-changing incidence of thyroid cancer. Nat Rev Endocrinol. 2020;16(11):617-618. DOI: 10.1038/s41574-020-00414-9.
- Cho A, Chang Y, Ahn J, Shin H, Ryu S. Cigarette smoking and thyroid cancer risk: a cohort study. Br J Cancer. 2018;119(5):638-645. DOI: 10.1038/ s41416-018-0224-5.
- Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, et al. 2021 American Thyroid Association Guidelines for Man agement of Patients with Anaplastic Thyroid Cancer. Thyroid. 2021;31(3):337-386. DOI: 10.1089/thy.2020.0944. Erratum in: Thyroid. 2021;31(10):1606-1607. DOI: 10.1089/thy.2020.0944.correx.
- Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016;26(1):1-133. DOI: 10.1089/thy.2015.0020.
- Winder M, Kosztyła Z, Boral A, Kocełak P, Chudek J. The Impact of Iodine Concentration Disorders on Health and Cancer. Nutrients. 2022;14(11):2209. DOI: 10.3390/nu14112209.
Publication of the article:
«Bulletin of problems biology and medicine», 2026 Issue 1, 180, 521-533 pages, index UDC 616.441-006:615.849-036.8-084