Ksenchyn O. O., Paliy I. G., Zaika S. V

CLINICAL AND EXPERIMENTAL MEDICINE

Scentific article

The standard for instrumental diagnosis of GERD is upper endoscopy and esophageal impedance-pH monitoring, but the above diagnostic methods are expensive, not always available, difficult to tolerate patients, which complicates their use in routine practice. An acceptable variant of objective diagnostic technique can be questionnaires. The purpose of the study was to study the diagnostic capabilities of GerdQ, GSRS questionnaires and to study the quality of life according to the SF-36 questionnaire in patients with GERD, depending on the presence of concomitant hypertension. Object and methods. The study involved 125 patients (54 men and 71 women), mean age50±1.4 years, divided into 3 groups: practically healthy, patients with GERD, patients with GERD in combination with hypertension. All patients were tested with using GerdQ and GSRS questionnaires, the MOS SF-36 questionnaire was used to determine the quality of life. Results and discussion. In groups of patients with GERD and GERD with concomitant hypertension, the results of the GerdQ questionnaire were not significantly different (p> 0.05), and no significant difference in the severity of the reflux syndrome according to the GSRS questionnaire was also found (p> 0.05). According to the quality of life assessment, the presence of concomitant hypertension significantly decreased (p <0.05) the level of physical functioning, the level of emotional functioning and the level of psychological health in patients with GERD. Conclusions. In groups of patients with GERD and GERD with concomitant hypertension, the results of the GerdQ and GSRS questionnaires were not significantly different, this makes them possible to use for the routine diagnostic of GERD, regardless of the presence of concomitant hypertension. Assessment of quality of life revealed no reliable influence on its level of presence of GERD, at the same time established a significant negative impact of concomitant hypertension on the physical and mental component of health in patients with GERD.

gastroesophageal reflux disease, hypertension, questionnaires, quality of life.

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«Bulletin of problems biology and medicine» Issue 4 Part 2 (154), 2019 year, 120-125 pages, index UDK 616.329/33-002+616.12-008.331

10.29254/2077-4214-2019-4-2-154-120-125