Shepitko K. V.

LITERATURE REVIEWS

Scentific article

The article is devoted to the problems of using the method of treating the small intestine pathologies by means of cryopreserved placenta products transplantation. The urgency of the problem is based on an analysis of the digestive diseases incidence among the population. A general analysis of the gastrointestinal diseases incidence among the population of Ukraine is presented. The total bulk of pharmacological drugs do not solve the primary task – restoration of the cellular composition in the damaged homologous organ. In addition to the development and use of synthesized pharmacological drugs for the gastrointestinal tract pathology correction, there is an ever growing focus on the cell and tissue transplantation and regeneration therapy, based on the use of allo- and xenogenic tissues and cells of embryo-fetoplacental complex. Due to the transplantation of placental and fetal cells and tissues, new possibilities have been used in the treatment of intractable and exigent conditions, particularly in cases of dystrophic processes, metabolic pathology, endocrine insufficiency, in combat injuries as a consequence of combat actions and in catastrophes. The purpose set for a group of UMSA researchers was to establish changes in the morphometric parameters of the duodenum, jejunum and ileum wall in rats with administration of cryopreserved placenta for its further use in medical emergency cases. The study of changes in the morphometric parameters of the small intestine wall’s different layers after administration of cryopreserved placenta is an urgent problem of modern experimental medicine, and can serve as a key for the proper treatment and prevention of bowel diseases and in exigent conditions caused by emergency situations.

diseases of the small intestine, exigent conditions, cryopreserved placenta, morphological parameters, duodenum, jejunum and ileum.

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«Bulletin of problems biology and medicine» Issue 4 Part 2 (154), 2019 year, 56-61 pages, index UDK 616.340:615.368:618.36-026.656

10.29254/2077-4214-2019-4-2-154-56-61