Soltys R. M., Khmara T. V.

MORPHOMETRIC CHARACTERISTICS AND INDIVIDUAL ANATOMICAL VARIABILITY OF THE INFRATEMPORAL FOSSA IN THE PRENATAL PERIOD OF HUMAN ONTOGENESIS

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Soltys R. M., Khmara T. V.

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MORPHOLOGY

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Scientific article

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Studying the prenatal morphogenesis of the facial skeleton is critical for understanding the formation of congenital malformations and improving prenatal diagnostic methods. The infratemporal fossa, a complex anatomical space containing neurovascular structures and the buccal fat pad, requires detailed morphometric analysis throughout fetal development. The aim is to determine the growth patterns of the linear parameters of the human infratemporal fossa in the fetal period of human ontogenesis using regression analysis. The study was conducted on the study of 72 computed tomograms (CT) of human fetuses with a parieto-coccygeal length (PCL) of 81.0–375.0 mm without signs of pathology. The anterior-posterior size, width and height of the infratemporal fossa were measured using digital morphometry software Radiant DICOM Viewer. CT scans were used from the collection of the Department of Anatomy, Clinical Anatomy and Operative Surgery of the Bukovinian State Medical University (BSMU). The work was carried out in accordance with international and national ethical standards and approved by the BSMU Biomedical Ethics Committee. It was established that the linear parameters of the infratemporal fossa demonstrate steady growth strongly correlated with the fetus’s PCL. The most intense dynamics were observed for the anteroposterior dimension (y=0,103x–6,43), the growth rate of which is nearly 1.5 times higher than that of the width (y=0,067x–4,28) and height (y=0,062x–3,72). The period of most active morphogenesis occurs within the PCL range of 230.0–255.0 mm, where the length of the fossa reaches peak values of 18.0–21.0 mm. The moving average method confirmed the reliability of the linear trend and neutralized the influence of individual anatomical variability. The formation of the infratemporal fossa during the prenatal period is characterized by priority growth in the sagittal plane. The obtained regression equations objectively reflect the rates of fetal development of the lateral skull norm and can serve as normative benchmarks for prenatal diagnosis and reconstructive surgery.

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Publication of the article:

«Bulletin of problems biology and medicine», 2026 Issue 2, 181, 257-263 pages, index UDC 611.714.013-053.13:611.92-071.3

DOI:

10.29254/2077-4214-2026-2-181-257-263