Nekhanevych O. B., Vasilchenko V. S.

QUALITY OF LIFE PROBLEMS ASSOCIATED WITH BLADDER FUNCTION DISORDERS IN PATIENTS WITH SPINAL CORD INJURY

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About the author:

Nekhanevych O. B., Vasilchenko V. S.

Heading:

CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

Annotation:

Spinal cord injury (SCI) is often accompanied by complex disorders of the pelvic organs, in particular the bladder, which significantly affects the quality of life of patients. Such disorders cause physical and psychological discomfort, which, together with social restrictions, creates barriers to autonomy, participation in everyday activities and professional fulfillment. In the conditions of Ukraine, this problem remains insufficiently studied, which reduces the effectiveness of medical care and rehabilitation programs. The aim of the study was to establish the degree of connection and influence of the type of bladder emptying on the limitations in everyday activity and quality of life in patients with impaired urinary system function after spinal cord injury. To achieve the objectives set in the scientific work, a survey was conducted in 2024 of 20 patients with spinal cord injury and associated urinary disorders aged 24 to 66 years, who were divided into 2 groups: 9 participants with preserved physiological bladder emptying function (group 1) and 11 people on intermittent catheterization (group 2). Participants were asked to undergo a comprehensive assessment of quality of life and functional status by completing three tools: standardized questionnaires WHODAS 2.0 (36-item) and WHOQOL-BREF (ukr), as well as the author's developed scale for assessing bladder and urinary control disorders. Individuals from group 2 were found to have 36.2% more limitations in daily activities and, on average, 42.8% lower quality of life indicators. The presented analysis emphasizes the need for a comprehensive approach to the rehabilitation of such individuals, improving multidisciplinary care and developing personalized support strategies that will contribute to improving the quality of life and social integration.

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Bibliography:

1. Grossman SD, Wolfe BB, Yasuda RP, Wrathall JR. Alterations in AMPA receptor subunit expression after experimental spinal cord contusion injury. J Neurosci. 1999;19(14):5711-20. DOI: 10.1523/JNEUROSCI.19-14-05711. 1999.
2. Chen YC, Kuo HC. Risk factors of video urodynamics and bladder management for long-term complications in patients with chronic spinal cord injury. Sci Rep. 2024;14(1):12632. DOI: 10.1038/s41598-024-63441-0.
3. Moghalu O, Stoffel JT, Elliott S, Welk B, Lenherr S, Herrick J, et al. Psychosocial aspects of health-related quality of life and the association with patient-reported bladder symptoms and satisfaction after spinal cord injury. Spinal Cord. 2021;59(9):987-96. DOI: 10.1038/s41393-020-00609-7.
4. Crescenze IM, Myers JB, Lenherr SM, Elliott SP, Welk B, Qin Y, et al. Predictors of low urinary quality of life in spinal cord injury patients on clean intermittent catheterization. Neurourol Urodyn. 2019;38(5):1332-8. DOI: 10.1002/nau.23983.
5. Moghalu O, Stoffel JT, Elliott SP, Welk B, Zhang C, Presson A, et al. Time-related changes in patient-reported bladder symptoms and satisfaction after spinal cord injury. J Urol. 2022;207(2):392-9. DOI: 10.1097/JU.00000 00000002228.
6. Nekhanevych O, Smyrnova O, Vasylchenko V, Losieva R. Problemy ta perspektyvy fizychnoi reabilitatsii patsientiv z porushenniamy tazovykh orhaniv vnaslidok travm spynnoho mozku v ukraini. Neonatolohiia Khirurhiia Ta Perynatalna Medytsyna. 2024;14(2(52)):151-6. DOI: 10.24061/2413-4260.XIV.2.52.2024.21. [in Ukrainian].
7. Ustun TB, Kostanjsek N, Chatterji S, Rehm J, editors. Measuring Health and Disability: Manual for WHO Disability Assessment Schedule (WHODAS 2.0). Geneva: World Health Organization; 2010.
8. World Health Organization. WHOQOL-BREF: Ukrainian version. Geneva: World Health Organization; 2020. Available from: https://www. who. int/tools/whoqol/whoqol-bref/docs/default-source/publishing-policies/ whoqol-bref/ukrainian-whoqol-bref.
9. Voloshchenko Yu. Yakist zhyttia molodykh liudei: perevirka adaptatsii ukrainskoi versii korotkoho opytuvalnyka yakosti zhyttia (WHOQOL- BREF UKR) sered studentiv pershoho kursu Kyivskoho universytetu imeni Borysa Hrinchenka. Sportyvna Nauka Ta Zdorov’ia Liudyny. 2023;2(10). DOI: 10.28925/2664-2069.2023.24. [in Ukrainian].
10. Perrin A, Corcos J. The Utility of Urodynamic Studies in Neuro-Urological Patients. Biomedicines. 2023;11(4):1134. DOI: 10.3390/biomedicines1104 1134.
11. Goraczko A, Zurek A, Lachowicz M, Kujawa K, Zurek G. The Relationship between Cognitive Performance and Quality of Life in Elite Athletes after Spinal Cord Injury. Int J Environ Res Public Health. 2022;19(2):948. DOI: 10.3390/ijerph19020948.
12. Sargent L, Smitherman J, Sorenson M, Brown R, Starkweather A. Cognitive and physical impairment in spinal cord injury: A scoping review and call for new understanding. J Spinal Cord Med. 2023;46(3):343-366. DOI: 10.1080/10790268.2022.2134634.
13. Makkar V, Pandurangi A, Makkar V, Hani U, Mahadevaiah M, Pandurangi S. Psychological Well-being and Quality of Life for Patients with Stable Spinal Cord Injury: A Cross-sectional Study. Int J Appl Basic Med Res. 2025;15(1):43-48. DOI: 10.4103/ijabmr.ijabmr_428_24.
14. Gurcay E, Bal A, Eksioglu E, Cakci A. Quality of life in patients with spinal cord injury. Int J Rehabil Res. 2010;33(4):356-358. DOI: 10.1097/ MRR. 0b013e328338b034.
15. Elmelund M, Klarskov N, Biering-Sørensen F. Prevalence of urinary incontinence in women with spinal cord injury. Spinal Cord. 2018;56(12):1124-1133. DOI: 10.1038/s41393-018-0157-0.
16. Viaene AM, Roggeman S, Vanhaute OA, Raes A, Colman R, Everaert K. Nocturnal bladder emptying and Quality of Life in patients with spinal cord injury. Eur J Phys Rehabil Med. 2022;58(3):397-404. DOI: 10.23736/S1973-9087.21.07104-5.
17. Hicken BL, Putzke JD, Richards JS. Bladder management and quality of life after spinal cord injury. Am J Phys Med Rehabil. 2001;80(12):916- 922. DOI: 10.1097/00002060-200112000-00008.
18. Diop M, Epstein D. A Systematic Review of the Impact of Spinal Cord Injury on Costs and Health-Related Quality of Life. PharmacoEconomics Open. 2024;8(6):793-808. DOI: 10.1007/s41669-024-00517-3.
19. Jörgensen S, Hedgren L, Sundelin A, Lexell J. Global and domain-specific life satisfaction among older adults with long-term spinal cord injury. J Spinal Cord Med. 2021;44(2):322-330. DOI: 10.1080/10790268.2019.1610618.

Publication of the article:

«Bulletin of problems biology and medicine», 2025 Issue 4, 179, 166-177 pages, index UDC 616.832-001-06:616.62-008.22]-092.11-036.82

DOI:

10.29254/2077-4214-2025-4-179-166-177