Fomina L. V., Kushnir N. M., Kushnir V. O., Shapoval O. M.

CHRONIC DERMATOSES: PATHOGENESIS, DIAGNOSIS, AND TREATMENT IN WARTIME UKRAINE COMPARED TO GLOBAL PRACTICES (A LITERATURE REVIEW)

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About the author:

Fomina L. V., Kushnir N. M., Kushnir V. O., Shapoval O. M.

Heading:

LITERATURE REVIEWS

Type of article:

Scientific article

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Chronic dermatoses are one of the most common groups of dermatological diseases that significantly affect patients' quality of life. This paper presents modern views on the pathogenesis, diagnostic approaches, and current treatment methods for diseases such as psoriasis, atopic dermatitis, and eczema, with a focus on the conditions of martial law in Ukraine and a comparison with global experience. The article highlights the challenges faced by military and civilian doctors in providing medical care under extreme conditions. The discrepancies in disease classification between civilian and military medical guidelines create additional challenges. The frequency and severity of these diseases have also increased among servicemen. Our review emphasizes the importance of integrating international experience and practices to improve the management of chronic dermatoses in Ukraine. It also discusses the unique stress factors experienced by military personnel, such as poor sanitary conditions, limited access to specialized care, and prolonged exposure to psychological stress. Special attention is given to the development of innovative strategies, including mobile medical teams, the use of telemedicine, and the introduction of educational programs to improve dermatological expertise among medical personnel. Furthermore, the analysis highlights the necessity of psychological support as an integral part of therapy to improve the overall health outcomes of patients.

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Bibliography:

1. Nestle FO, Kaplan DH, Barker J. Psoriasis. New England Journal of Medicine. 2009;361(5):496-509. DOI: https://doi.org/10.1056/NEJMra0804595.
2. Bieber T. Atopic dermatitis. New England Journal of Medicine. 2008;358(14):1483-1494. DOI: https://doi.org/10.1056/NEJMra074081.
3. Boguniewicz M, Leung DY. Atopic dermatitis: a disease of altered skin barrier and immune dysregulation. Immunological Reviews. 2011;242(1):233-246. DOI: https://doi.org/10.1111/j.1600-065X.2011.01027.x.
4. European Dermatology Forum. Guidelines for the treatment of atopic eczema. European Journal of Dermatology. 2018;28(2):156-172. DOI: https://doi.org/10.1684/ejd.2018.3285.
5. Silverberg JI, Hanifin JM. Adult eczema prevalence and associations with asthma and other health and demographic factors: a US populationbased study. Journal of Allergy and Clinical Immunology. 2013;132(5):1132-1138. DOI: https://doi.org/10.1016/j.jaci.2013.08.031.
6. Langan SM, Irvine AD, Weidinger S. Atopic dermatitis. Lancet. 2020;396(10247):345-360. DOI: https://doi.org/10.1016/S0140-6736(20)31286-1.
7. Smith CH, Anstey AV, Barker JN. British Association of Dermatologists guidelines for biologic interventions for psoriasis 2020. British Journal of Dermatology. 2020;183(4):628-637. DOI: https://doi.org/10.1111/bjd.19039.
8. Foley P, Zuo Y, Plunkett A, Merlin K, Marks R. The frequency of common skin conditions in preschool-aged children in Australia. Archives of Dermatology. 2020;139(3):318-322. DOI: https://doi.org/10.1001/archderm.139.3.318.
9. Barker JN, Smith CH, Anstey AV. Psoriasis treatment guidelines in 2021: A global overview. Dermatologic Clinics. 2021;39(2):105-112. DOI: https://doi.org/10.1016/j.det.2021.02.001.
10. Nast A, Smith C, Spuls PI, Avila Valle G, Bata-Csörgö Z, Boonen H, et al. EuroGuiDerm Guideline on the systemic treatment of Psoriasis vulgaris – Part 2: specific clinical and comorbid situations. Journal of the European Academy of Dermatology and Venereology. 2021;35:281- 317. DOI: https://doi.org/10.1111/jdv.16926.
11. Yolanda BB, Susan SJ, Montserrat M, Christoph RM. Psoriasis and risk of incident cancer: an inception cohort study with a nested casecontrol analysis. Journal of Investigative Dermatology. 2020;129(11):2604-2612. DOI: https://doi.org/10.1038/jid.2009.113.
12. Gelfand JM, Dommasch ED, Shin DB, Azfar RS, Kurd SK, Wang X, et al. The risk of stroke in patients with psoriasis. Journal of Investigative Dermatology. 2009;129(10):2411-2418. DOI: https://doi.org/10.1038/jid.2009.112.
13. Griffiths CEM, Armstrong AW, Gudjonsson JE, Barker JNWN. Psoriasis. Lancet. 2021;397(10281):1301-1315. DOI: https://doi.org/10.1016/S0140-6736(20)32549-6.
14. Chiricozzi A, Maurelli M, Girolomoni G. Targeting IL-4 for the treatment of atopic dermatitis. Immunotargets and Therapy. 2020;9:151-156. DOI: https://doi.org/10.2147/ITT.S260370.
15. Eichenfield LF, Tom WL, Chamlin SL, Feldman SR, Hanifin JM, Simpson EL, et al. Guidelines of care for the management of atopic dermatitis. Journal of the American Academy of Dermatology. 2014;70(2):338-351. DOI: https://doi.org/10.1016/j.jaad.2013.10.010.
16. Paller AS, Spergel JM, Mina-Osorio P, Irvine AD. The atopic march and its temporal relationship to food allergy. Allergy. 2019;74(10):1843- 1855. DOI: https://doi.org/10.1111/all.13810.
17. Sidbury R, Davis DM, Cohen DE. Guidelines of care for the management of atopic dermatitis: section 3. Journal of the American Academy of Dermatology. 2014;71(2):327-349. DOI: https://doi.org/10.1016/j.jaad.2014.03.030.
18. Takeshita J, Grewal S, Langan SM. Psoriasis and comorbid diseases: epidemiology. Journal of the American Academy of Dermatology. 2017;76(3):377-390. DOI: https://doi.org/10.1016/j.jaad.2016.07.064.
19. Drucker AM, Wang AR, Li WQ, Sevetson E, Block JK, Qureshi AA. The burden of atopic dermatitis: summary of a report for the National Eczema Association. Journal of Investigative Dermatology. 2017;137(1):26-30. DOI: https://doi.org/10.1016/j.jid.2016.07.012.
20. Weidinger S, Novak N. Atopic dermatitis. Lancet. 2016;387(10023):1109-1122. DOI: https://doi.org/10.1016/S0140-6736(15)00149-X.
21. Ministerstvo oborony Ukrayiny. Nakaz № 402 Pro zatverdzhennia Polozhennia pro viiskovo-likarsku ekspertyzu v Zbroinykh Sylakh Ukrainy. Kyyiv: Ministerstvo oborony Ukrayiny; 2008. [in Ukrainian].
22. Ministerstvo oborony Ukrayiny. Nakaz № 262 Pro zatverdzhennia zmin do Polozhennia pro viiskovo-likarsku ekspertyzu v Zbroinykh Sylakh Ukrainy. Kyyiv: Ministerstvo oborony Ukrayiny; 2024. [in Ukrainian].
23. Ministerstvo okhorony zdorov’ya Ukrayiny. Nakaz № 762 Pro zatverdzhennya ta vprovadzhennya medyko-tekhnolohichnykh dokumentiv zi standartyzatsiyi medychnoyi dopomohy pry psoriazi, vklyuchayuchy psoriatychni artropatiyi. Kyyiv: Ministerstvo khorony zdorov’ya Ukrayiny; 2015. Dostupno: https://zakon.rada.gov.ua/rada/show/v0762282-15#Text. [in Ukrainian].
24. Ministerstvo okhorony zdorov’ya Ukrayiny. Nakaz № 670 Pro zatverdzhennya ta vprovadzhennya medyko-tekhnolohichnykh dokumentiv zi standartyzatsiyi medychnoyi dopomohy pry atopichnomu dermatyti. Kyyiv: Ministerstvo khorony zdorov’ya Ukrayiny; 2016. [in Ukrainian].
25. Armstrong AW, Read C. Pathophysiology, clinical presentation, and treatment of psoriasis: A review. JAMA. 2020;323(19):1945-1960. DOI: https://doi.org/10.1001/jama.2020.4006.

Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 4, 175, 146-153 pages, index UDC 616.5-002.828-07:616-083(477.8)

DOI:

10.29254/2077-4214-2024-4-175-146-153