Pidvalna U. Ye.

CORRELATION OF THE DIAMETER OF THE ASCENDING AORTIC WITH AGE AND ANTHROPOMETRIC PARAMETERS IN MEN WITH MARFAN SYNDROME: A CT STUDY

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About the author:

Pidvalna U. Ye.

Heading:

MORPHOLOGY

Type of article:

Scientific article

Annotation:

This study explores the correlation between the diameter of the ascending aortic with anthropometric parameters and age in Ukrainian men with Marfan syndrome. DICOM files from ECG-triggered contrast-enhanced computed tomography scans were used with measuring the diameters of the ascending aortic segments. Diameter of the aorta were measured at the levels of: aortic annulus, sinotubular junction, sinuses of Valsalva, at the level of pulmonary trunk bifurcation, before the brachiocephalic trunk and maximal ascending aortic diameter. Marfan syndrome diagnose was primarily established by the Ghent nosology. Statistical analyses, including Student’s t-test, Pearson’s linear correlation, and multiple regression, were conducted. The study found a direct correlation between height and the diameter of the aorta at the sinotubular junction and an inverse correlation between height and the diameter of the high-ascending aortic. No significant correlations were found between the diameters of the ascending aortic and age, weight, body mass index or body surface area. The results suggest that in men with Marfan syndrome, the diameter of the ascending aortic at the sinotubular junction increases with height. In contrast, the high-ascending aortic diameter decreases, with other factors showing no significant impact.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 3, 174, 310-317 pages, index UDC 616.132.13:616-018.2:572.511.4]-055.1

DOI:

10.29254/2077-4214-2024-3-174-310-317