MONITORING OF MODERN VIEWS ON THE CAUSES AND MECHANISMS OF PERIODONTAL DISEASE DEVELOPMENT

  2. 2024
  3. MONITORING OF MODERN VIEWS ON THE CAUSES AND MECHANISMS OF PERIODONTAL DISEASE DEVELOPMENT

Hasiuk N. V., Misterman I. P., Radchuk V. B., Bozhik S. S.

MONITORING OF MODERN VIEWS ON THE CAUSES AND MECHANISMS OF PERIODONTAL DISEASE DEVELOPMENT

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About the author:

Hasiuk N. V., Misterman I. P., Radchuk V. B., Bozhik S. S.

Heading:

LITERATURE REVIEWS

Type of article:

Scientific article

Annotation:

Periodontal diseases are accompanied by a complex of morphological and functional changes in the dentoalveolar system and the body as a whole and are an urgent problem of modern dentistry. The purpose is to monitor current views on the aetiology and pathogenesis of periodontal diseases based on the results of the analysis of medical and scientific literature based on the databases Scopus, Web of Science, MedLine, PubMed, and NCBI over the past ten years. According to the study's results, a number of etiological factors and links of pathogenesis were identified from the standpoint of modern science. The key factors are disorders of the immune system, namely its homeostasis, metabolic disorders, genetic factors, and the state of individual oral hygiene. The study indicates a significant role of systemic immunological changes, which result in a cytokine attack of the body as a whole and periodontal tissues in particular. However, only a few studies in the scientific literature outline the role of immunological changes at the local level, namely, from the side of the components that ensure oral homeostasis. The study of the latter will enable the development and implementation of a system for preventing inflammatory diseases of periodontal tissues in young patients without concomitant somatic pathology. The above gives a clear understanding of the cause-and-effect relationship between the etiological factors of periodontal diseases and the links of pathogenesis, which in turn creates the prerequisites for the development of more effective ways to prevent and treat this group of diseases.

Tags:

antigens, dentistry, inflammatory process, periodontal disease, periodontium

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Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 2, 173, 23-32 pages, index UDC 616.311.2/314.17-02-036

DOI:

10.29254/2077-4214-2024-2-173-23-32

2024 Issue 2, 173
antigens dentistry inflammatory process periodontal disease periodontium
27.06.2024
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