Novykov K. R., Lytvynenko L. P., Fylenko B. M., Roiko N. V., Prylutskyi O. K., Proskurnia S. A.

BREAST CANCER IN THE POLTAVA REGION: CLINICAL AND MORPHOLOGICAL ASPECTS

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Novykov K. R., Lytvynenko L. P., Fylenko B. M., Roiko N. V., Prylutskyi O. K., Proskurnia S. A.

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PROSPECTS FOR THE DEVELOPMENT OF MORPHOLOGICAL AND CLINICAL RESEARCH

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Scientific article

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The aim of the study was to analyse the clinical and epidemiological and some pathomorphological aspects of breast cancer based on a retrospective analysis of postoperative material. We analysed 238 protocols of pathological reports and microscopic examination of postoperative breast cancer material. During the study, the age of patients, the degree of differentiation, the histological variant of the tumour and their relationship were determined. It was found that there was no correlation between the degree of cancer differentiation and the age of the patients. It was determined that the size of the tumour at the time of its detection has a direct correlation with the degree of its differentiation. The histological examination revealed that all carcinomas, regardless of the degree of differentiation, were characterised by invasion of the walls of blood and lymphatic vessels. Highly differentiated cancer did not metastasise, мoderately differentiated cancer metastasised in 52.4% of cases, and low-grade cancer metastasised in 59% of cases. Different histological types of breast cancer demonstrate heterogeneous clinical and pathological characteristics. It was found that the size of the tumour, invasion of lymphatic and blood vessels, and metastasis are correlated with the degree of differentiation.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 2, 173, addition, 9-12 pages, index UDC 618.19-006(477.53)

DOI:

10.29254/2523-4110-2024-2-173/addition-9-12