Kalyta V. I., Dziuryi I. V., Boyko S. M., Truba Ia. P., Plyska O. I., Lazoryshynets V. V.
EXPERIENCE OF ANAESTHETIC MANAGEMENT AND INTENSIVE CARE IN PATIENTS WITH SINGLE VENTRICLE PHYSIOLOGY
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About the author:
Kalyta V. I., Dziuryi I. V., Boyko S. M., Truba Ia. P., Plyska O. I., Lazoryshynets V. V.
Heading:
CLINICAL AND EXPERIMENTAL MEDICINE
Type of article:
Scientific article
Annotation:
Single ventricle physiology is a term used to describe a group of complex congenital heart defects with a single functioning ventricle. The survival of such patients depends on mixing systemic deoxygenated blood with oxygenated pulmonary venous blood and on an open channel for redirecting the mixed blood to the small and systemic circulation. Palliative treatment of patients with single ventricle physiology aims to transfer the single ventricle circulation from parallel to sequential and includes three stages, culminating in total Fontan cavopulmonary anastomosis. Bidirectional cavopulmonary anastomosis is the second stage of haemodynamic correction in patients with single ventricle physiology. It eliminates parallel circulation and ventricular volume overload but not cyanosis. The study aims to describe the experience of anaesthetic management and intensive care in patients with single ventricle physiology at the stage of haemodynamic correction. From 1996 to 2022, 104 patients with a single ventricle underwent bidirectional cavopulmonary anastomosis at the Amosov National Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine. The main methods used to determine the defect and assess postoperative outcomes were cardiac cavity sounding and echocardiography. All patients were divided into two age groups. Group A included 57 patients (55%) aged 3 to 36 months, and Group B consisted of 47 patients (45%) over 36 months. There is a lower need for prolonged intensive care, a lower number and less severe severity of postoperative complications, a longer overall ICU stay, and a higher average systemic saturation in patients who were operated on between the ages of 3 and 36 months due to the peculiarities of haemodynamic and adaptive processes. The choice of age and tactics for hemodynamic correction in patients with single ventricle physiology directly affects the perioperative period and the results of palliative treatment.
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Bibliography:
- Hoffman JI, Kaplan S. The incidence of congenital heart disease. J Am Coll Cardiol. 2002 Jun 19;39(12):1890-900. DOI: https://doi. org/10.1016/s0735-1097(02)01886-7.
- Harvey W. Exercitatio anatomica de motu cordis et sanguinis in animalibus. Thomas; 1970. 126 p.
- Florencia-Heredia M. Ventrículo único. Cirugía de Glenn y Fontan. Rev Latinoam Tecnol Extracorp. 2007;14:7-25.
- Jacobs ML, Anderson RH. Nomenclature of the functionally univentricular heart. Cardiol Young. 2006;16(1):3-8. DOI: https://10.1017/ S104795110 500226X.
- Edelson JB, Ravishankar C, Griffis H, Zhang X, Faerber J, Gardner MM, et al. A Comparison of Bidirectional Glenn vs. Hemi-Fontan Procedure: An Analysis of the Single Ventricle Reconstruction Trial Public Use Dataset. Pediatr Cardiol. 2020;41(6):1166-72. DOI: https://doi. org/10.1007/s00246-020-02371-6.
- Sharma R. The bidirectional Glenn shunt for univentricular hearts. Indian J Thorac Cardiovasc Surg. 2018;34(4):453-456. DOI: https://doi. org/10.1007/ s12055-018-0653-z.
- Carlon C, Mondini P, de Marchi R. Surgical treatment of some cardiovascular diseases. J Int Coll Surg. 1951;16(1):1-11.
- Haller J, Adkins J, Worthington M, Rauenhorst J. Experimental studies on permanent bypass of the right heart. Surgery. 1966;59(6):1128- 1132.
- Fontan F, Baudet E. Surgical repair of tricuspid atresia. Thorax. 1971;26:240-8., 99.
- Salim MA, DiSessa TG, Arheart KL, Alpert BS. Contribution of superior vena caval flow to total cardiac output in children. A Doppler echocardiographic study. Circulation. 1995;92(7):1860-1865. DOI: https://doi.org/10.1161/ 01.cir.92.7.1860.
- Liu Y, Chen S, Zühlke L, Black GC, Choy MK, Li N, et al. Global birth prevalence of congenital heart defects 1970–2017: updated systematic review and meta-analysis of 260 studies. Int J Epidemiol. 2019;48(2):455-463.
- Walker SG, Stuth EA. Single-ventricle physiology: perioperative implications. Seminars in Pediatric Surgery. 2004 Aug;13(3):188-202. DOI: https://doi.org/10.1053/j.sempedsurg.2004.04.005.
- Spector LG, Menk JS, Knight JH, McCracken C, Thomas AS, Vinocur JM, et al. Trends in long-term mortality after congenital heart surgery. J Am Coll Cardiol. 2018;71:2434-2446.
- Minocha P, Phoon C. Tricuspid atresia [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. Available from: .
- Greaney D, Honjo O, O’Leary JD. The single ventricle pathway in paediatrics for anaesthetists. BJA Educ. 2019 May;19(5):144-150. DOI: https://doi. org/10.1016/j.bjae.2019.01.008.
- Holst KA, Dearani JA, Said S, Pike RB, Connolly HM, Cannon BC, et al. Improving Results of Surgery for Ebstein Anomaly: Where Are We After 235 Cone Repairs? Ann Thorac Surg. 2018 Jan;105(1):160-8. DOI: https://doi.org/10.1016/j.athoracsur.2017.09.058.
- King G, Ayer J, Celermajer D, Zentner D, Justo R, Disney P, et al. Atrioventricular valve failure in Fontan palliation. J Am Coll Cardiol. 2019;73:810-822.
- Joshi H, Germeroth DR. Single Ventricle And Anesthesia Management. Treasure Island (FL): StatPearls Publishing; 2022.
- Martin BJ, De Villiers Jonker I, Joffe AR, Bond GY, Acton BV, Ross DB, et al. Hypoplastic left heart syndrome is not associated with worse clinical or neurodevelopmental outcomes than other cardiac pathologies after the Norwood-Sano operation. Pediatr Cardiol. 2017;38:922- 931.
Publication of the article:
«Bulletin of problems biology and medicine», 2023 Issue 4, 171, 199-209 pages, index UDC 616.124-007.2-053.1-089:616-089.5