Donchenko S. V., Bilash S. M.
IMMUNOHISTOCHEMICAL CHARACTERISTICS OF STRUCTURAL CHANGES IN THE CORTEX AND MEDULLA OF THE ADRENAL GLANDS UNDER THE INFLUENCE OF A FOOD ADDITIVE COMPLEX
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About the author:
Donchenko S. V., Bilash S. M.
Heading:
MORPHOLOGY
Type of article:
Scientific article
Annotation:
The importance of taste plays a significant role in everyone's life. Our taste buds play an essential role in recognizing flavors, determining the suitability of food, protecting us from harmful substances, and regulating our food intake. People always enjoy tasty food, and sweet foods contribute to positive emotions. Every day, we consume food containing a significant amount of food additives and preservatives without even thinking about their possible health consequences. Tasty but unhealthy food has become popular and affordable, and we often cannot resist the temptation to eat it. Many food additives are created to meet the needs of the food industry, as they differ from cooking at home and require products that need to be stored in a marketable condition for longer. However, these additives must be safe for consumers' health and should not mislead them. Today, there are many food additives that consumers are unaware of but which can negatively affect human organs, including the adrenal glands. Some of the most common food additives under investigation include monosodium glutamate (E 621), monosodium nitrite (E 250), and Ponceau 4R (E 124). Consumption of a significant amount of food additives can have the following adverse effects: chest and abdominal pain, migraines, nausea, tachycardia, obesity, weakness, and allergic reactions. Particular attention should be paid to the impact of these supplements on the adrenal glands, as they can affect their function and contribute to cancer development. Research on adrenal morphology has been ongoing for many years. In recent decades, there has been an increase in adrenal pathology as the negative impact of external and internal factors increases, leading to disorders in their structure and function. The adrenal glands play an essential role in the hypothalamic-pituitary-adrenal system and are also endocrine organs. The interest in changes in the structure of the adrenal glands is still ongoing among experimental medicine and scientists. Thanks to the improvement of computer diagnostic methods, the possibility of detecting both hormonally active and inactive benign and malignant tumors in the adrenal glands is increasing. The most common endocrine disorders are hyperaldosteronism, adrenergic and estrogen imbalance. Computed tomography significantly improves the ability to detect tumors of various origins in the adrenal glands. Diagnosing and treating adrenal gland diseases are an urgent medical and social problem
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Bibliography:
- Pronina OM, Koptev MM, Bilash SM, Yeroshenko GA. Response of hemomicrocirculatory bed of internal organs on various external factors exposure based on the morphological research data. World of medicine and biology. 2018;1(63):153-7.
- Butnariu M, Sarac I. What is sodium glutamate and what effects it has on health. Journal of Applied Biotechnology and Bioengineering. 2019;6(5):223-6.
- Millan S, Satish L, Bera K, Sahoo H. Binding and inhibitory effect of the food colorants Sunset Yellow and Ponceau 4R on amyloid fibrillation of lysozyme. New Journal of Chemistry. 2019;9:3956-68.
- Wojciech P, Michael HR. A Text and Atlas: With Correlated Cell and Molecular Biology. 8th ed. USA: Wolters Kluwer Health Inc.; 2020. 606 p.
- Bilash SM, Donchenko SV, Pronina OM, Koptev MM, Oliinichenko YO, Onipko VV, et al. Morphometric features of the elements of the hemomicrocirculatory bed in the cortex of the adrenal glands influenced by the food additives complex. Wiadomosci Lekarskie. 2022 Jan; 75(6):1558-1563.
- Pronina OM, Bilash SM, Kobeniak MM, Koptev MM, Pirog-Zakaznikova AV, Onipko VV, et al. Morphometric features of the structural components of the hemomicrocirculatory bed in the perivulnar region of the caecum in wound defect sutured with polyfilament suture material. Wiadomości Lekarskie. 2021 Jan; 74(6):1382-1388.
- Bilash SM, Donchenko SV. Morfofunktsionalnyi stan nadnyrnykiv pry dii kompleksu kharchovykh dobavok (ohlyad literatury). Visnyk problem biolohii i medytsyny. 2020;3(157):13-19. [in Ukrainian]
- Donchenko SV, Bilash SM. Structural organization of the adrenal glands medulla of rats in normal and after influence of food additive complex. Visnyk problem biolohii i medytsyny. 2022;2(169):210-216.
- Yachmin AI, Kononov BS, Yeroshenko GA, Bilash SM, Bilash VP. A measure of the effect of complex food additives on rats’ adaptive responses. World of Medicine and Biology. 2020;1(71):232-235.
- Kononov BS. Strukturna orhanizatsiya mozochku laboratornykh tvaryn v normi ta u porivnyalʹno-vydovomu aspekti. Vísnik problem bíologii i meditsiny. 2020;4(158):272-276. [in Ukrainian].
- Oliynichenko YAO, Bilash SM, Pronina OM, Koptev MM, Oliynichenko MO, Bezeha OV, et al. Vplyv kompleksu kharchovykh dobavok na protsesy remodulyuvannya strukturnykh komponentiv tonkoho kyshechnyka, yak vazhlyva medyko-sotsialʹna problema suchasnoho stanu zabezpechennya hromadsʹkoho zdorovʺya naselennya Ukrayiny. Visnyk problem biolohiyi i medytsyny. 2021;3(161):65-70. [in Ukrainian].
- Bilash SM, Kononov BS, Pronina OM, Kononova MM, Bilash VP, Shostya AM, et al. Particularities associated with the expression of glial acidic fibrillary protein on the structural components of cerebellum of the rats influenced by the food additives complex. Wiadomości Lekarskie. 2021 June;74(6):1409-1413.
- Donchenko SV, Bilash SM. Structural organization of rats adrenal glands in normal state. Visnyk problem biolohii i medytsyny. 2022;4(167):291-295.
Publication of the article:
«Bulletin of problems biology and medicine», 2023 Issue 3, 170, 402-406 pages, index UDC 611.451/453-018-026.19:613.29
