STATE OF REGIONAL HEMODYNAMICS AND LEVEL OF ADAPTATION OF THE CARDIOVASCULAR SYSTEM IN PATIENTS WITH OPTIC NEURITIS

  2. 2023
  3. STATE OF REGIONAL HEMODYNAMICS AND LEVEL OF ADAPTATION OF THE CARDIOVASCULAR SYSTEM IN PATIENTS WITH OPTIC NEURITIS

Khramenko N. I.

STATE OF REGIONAL HEMODYNAMICS AND LEVEL OF ADAPTATION OF THE CARDIOVASCULAR SYSTEM IN PATIENTS WITH OPTIC NEURITIS

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About the author:

Khramenko N. I.

Heading:

CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

Annotation:

Vascular disorders in the optic neuritis (ON) due to the inflammatory process lead to ischemia and persistent trophic changes in the inner layers of the retina with the loss of retinal ganglion cell neurons. The regulatory influence of the autonomic nervous system (ANS) on the vascular system and its active participation in the inflammatory reaction is known. Purpose: to study the state of regional hemodynamics by the rheoophthalmography (ROG), the state of ANS by the heart rate variability (HRV) method and the level of adaptation potential (AP) of the cardiovascular system in patients with idiopatic ON and its complicated outcome. 27 women and 30 men (82 eyes) with idiopathic ON were examined in the Laboratory of Functional Methods Research of Vision. Control group - 27 healthy volunteers. ROG was performed on a computer rheographic complex (Reocom, Ukraine, Kharkiv) for the eye pulse blood filling examination. The state of ANS was analyzed by HRV. AP was calculated by the R. Baevsky formula. It was found out that the factor of ON course affected of the eye volumetric pulse blood filling (RQ‰) indicator): F=3.2, p=0.01. Intension of AP was more common in the group of the partial atrophy of optic nerve (PAON). Parasympathetic activity was increased by 36.8% according to the HF (%) indicator in PAON group, which apparently characterizes the end of the inflammation productive phase. Conclusions: the peculiarities of regional hemodynamics, the AP of the cardiovascular system and the regulation of the ANS in patients with ON and its outcome have been determined.

Tags:

adaptation potential, autonomic nervous system, eye hemodynamics, optic neuritis

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Publication of the article:

«Bulletin of problems biology and medicine», 2023 Issue 2, 169, 315-320 pages, index UDC 617.731-002+616.1+615.15

DOI:

10.29254/2077-4214-2023-2-169-315-320

2023 Issue 2, 169
adaptation potential autonomic nervous system eye hemodynamics optic neuritis
29.06.2023
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