ПЕДІАТРИЧНИЙ LONG COVID: СУЧАСНІ АСПЕКТИ, ПАТОГЕНЕЗ, КЛІНІКА, ДІАГНОСТИКА, ЛІКУВАННЯ (ОГЛЯД ЛІТЕРАТУРИ ТА ВЛАСНЕ СПОСТЕРЕЖЕННЯ)

Конюшевська А. А., Герасименко В. В., Кузеванова М. В., Сторожчук Ю. О.

ПЕДІАТРИЧНИЙ LONG COVID: СУЧАСНІ АСПЕКТИ, ПАТОГЕНЕЗ, КЛІНІКА, ДІАГНОСТИКА, ЛІКУВАННЯ (ОГЛЯД ЛІТЕРАТУРИ ТА ВЛАСНЕ СПОСТЕРЕЖЕННЯ)


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Про автора:

Конюшевська А. А., Герасименко В. В., Кузеванова М. В., Сторожчук Ю. О.

Рубрика:

ОГЛЯДИ ЛІТЕРАТУРИ

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Наукова стаття

Анотація:

Постковідний синдром є актуальною проблемою сучасної педіатрії. Клінічні симптоми Long COVID у дітей гетерогенні, неспецифічні, можуть відрізнятися за частотою та вираженістю, залежати від віку дитини. Більшість симптомів зменшуються з часом, однак можуть зберігатися упродовж року й довше, що здатне суттєво погіршувати повсякденне функціонування та якість життя дитини. Найпоширенішими проявами Long COVID у дітей є неврологічні та психіатричні симптоми, кардіореспіраторні порушення та симптоми ураження шлунково-кишкового тракту. Проведено аналіз літературних даних, присвячених COVID-19 і Long COVID у дітей. В огляді розглянуто ймовірний патогенез Long COVID, клінічні прояви, особливості перебігу захворювання у дітей, його поширеність, фактори ризику розвитку тривалого COVID, вплив різних вірусних варіантів SARS-CoV-2 з різною вірулентністю внаслідок мутацій, питання діагностики та лікування, вплив вакцинації, а також рекомендації щодо ведення дітей із Long COVID. На сьогодні опубліковано поодинокі дані щодо клінічних наслідків COVID-19 у дітей, які перенесли безсимптомні або легкі форми інфекції, що підлягає подальшому вивченню. Нами наведено власне клінічне спостереження підлітка з Long COVID. Розширення знань про клініку, особливості перебігу COVID у дітей, фактори ризику розвитку тривалих персистуючих симптомів, сприяє покращенню діагностики захворювання та тактики ведення пацієнтів. Велике значення має пошук маркерів, які можуть прогнозувати розвиток синдрому, допомагати в діагностиці та оцінювати ефективність терапії.

Теги:

групи ризику, діагностика, діти, клініка, тривалий COVID-19

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Публікація статті:

«Вісник проблем біології і медицини», 2025 Випуск 4, 179, 32-56 сторінки, код УДК 616.98:578.834]-053.2-092-06-07-085

DOI:

10.29254/2077-4214-2025-4-179-32-56

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