Tykhonova O. O., Sherstyuk O. O., Tarasenko Ya. A., Bilash V. P., Serbin S. I., Dubyna S. O., Tkachenko O. T

TYPICAL MORPHOLOGICAL CHARACTERISTICS OF THE SKIN STRUCTURE OF THE HAIR PART OF THE NORMAL HUMAN HEAD AND WITH HAIR LOSS

---

Show/Download

About the author:

Tykhonova O. O., Sherstyuk O. O., Tarasenko Ya. A., Bilash V. P., Serbin S. I., Dubyna S. O., Tkachenko O. T

Heading:

MORPHOLOGY

Type of article:

Scientific article

Annotation:

A research object is the shreds of skin of hairy region of head of human with ahair cover which was saved, and at the distinctly expressed phenomena of androgenic alopecium, and also tissue complexes of membranous skull of 5-mounth fetuses of human. It is set as a result of research, that in the skin of hairy region of head of human there are different populations of hair follicles, which differs in depth bedding of the root bulbs and by a tendency to the united association in triads, that is conditioned genetically and especially model expressed on the 5th month of fetal period. Complete loss of hairs due androgenic alopecium, points the skins of hairy region of head leads to compensatory reorganization, which is expressed in a substitution in the hypodermis of loose fibred connecting tissue by fatty tissue, vast excrescence in all layers skins of blood vessels, which the venous prevail among, and also in the considerable increase of concentration of sebharrouse glands in the reticulated layer of derma.

Tags:

Bibliography:

1. Kalyuzhna LD, Hrechansʹka LV, Petrenko AV. Systemna pidtrymka formuvannya ta rostu volossya pry alopetsiyakh i zakhvoryuvannyakh stryzhnya volosyny. Dermatolohiya ta venerolohiya. 2020;2:29-34. [in Ukrainian].
2. Ruk A, Dauber R. Bolezni volos i volosistoy chasti golovy. M: Meditsina; 1985. 528 s.
3. Drake LA, Dinehart SM, Farmer ER, Goltz RW, Graham GF, Hordinsky MK, et al. Guidelines of care for androgenetic alopecia. American Academy of Dermatology. J Am Acad Dermatol. 1996 Sep;35(3.1):465-9.
4. Bahriy MM, Dibrova VA, Popadynetsʹ OH, Hryshchuk MI. Metodyky morfolohichnykh doslidzhenʹ. Vinnytsya: Nova knyha; 2016. 328 s. [in Ukrainian].
5. Belokon’ SA, Vitko YuN, Tkachenko PI, Starchenko II, Hryn VH. Optimizatsiya issledovaniya strukturnykh elementov biologicheskikh tkaney na gistotopograficheskikh shlifakh. Molodoy uchenyy. 2014;15(74):134-7.
6. Hryn VH, Sherstyuk OO, Starchenko II, Prylutsʹkyy OK, vynakhidnyky; VDNZU «UMSA», patentovlasnyk. Sposib kompleksnoho morfolohichnoho doslidzhennya chervopodibnykh vidrostkiv lyudyny v epoksydniy smoli «EPON-812». Patent Ukrayiny na korysnu modelʹ № UA112472U. 2016 Hrud 26. [in Ukrainian].
7. Kostilenko YuP, Kovalov YeV. Metody raboty s polutonkimi epoksidnymi srezami v gistologicheskoy praktike. Arkhiv anatomii, gistologii i embriologii. 1978;75(12):68-72.
8. Kostilenko YuP, Boyko IV, Starchenko II. Metod izgotovleniya gistologicheskikh preparatov, ravnotsennykh polutonkim srezam bol’shoy obzornoy poverkhnosti, dlya mnogotselevykh morfologicheskikh issledovaniy. Morfologiya. 2007;5:94-6.
9. Kaufman KD. Androgen metabolism as it affects hair growth in androgenetic alopecia. Dermatol Clin. 1996 Oct;14(4):697-711. DOI: 10.1016/s0733-8635(05)70396-x.
10. Nestor MS, Ablon G, Gade A, Han H, Fischer DL. Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics. J Cosmet Dermatol. 2021 Dec;20(12):3759-3781. DOI: 10.1111/jocd.14537.
11. Shkodina AD, Tan SC, Hasan MM, Abdelgawad M, Chopra H, Bilal M, et al. Roles of clock genes in the pathogenesis of Parkinson’s disease. Ageing Res Rev. 2022 Feb;74:101554. DOI: 10.1016/j.arr.2021.101554.
12. Chen W, Yang CC, Tsai RY, Liao CY, Yen YT, Hung CL, et al. Expression of sex-determining genes in the scalp of men with androgenetic alopecia. Dermatology. 2007;214(3):199-204. DOI: 10.1159/000099583.
13. Chuong CM. Regenerative biology: new hair from healing wounds. Nature. 2007 May 17;447(7142):265-6. DOI: 10.1038/447265a.

Publication of the article:

«Bulletin of problems biology and medicine», 2023 Issue 3, 170, 417-422 pages, index UDC 611.77–02:611.781.1+616.594.1

DOI:

10.29254/2077-4214-2023-3-170-417-422