Slyusar N. A., Saltanova S. D.

THE CLINICAL COURSE OF FUNCTIONAL GASTROINTESTINAL DISORDERS ACCOMPANIED BY ABDOMINAL PAIN IN CHILDREN IN MARTIAL LAW

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Slyusar N. A., Saltanova S. D.

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PEDIATRICS

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Scientific article

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Functional gastrointestinal disorders (FGID) in children, according to their biopsychosocial model, occur as a result of the complex interaction of biological, psychoemotional and psychosocial factors through the gut-brain axis. Among school-age children, the most common are FGIDs accompanied by abdominal pain. For the third year, children in our country have been at the epicentre of martial law events due to russia's full-scale invasion of Ukraine, which is the most potent stress factor for them that contributes to the occurrence of FGID and/or negatively affects their clinical course. The aim of the study was to investigate the peculiarities of the clinical course of FGID accompanied by abdominal pain in children under martial law. One hundred two children aged 6-17 years with functional dyspepsia and irritable bowel syndrome were examined. The study examined the features of pain and dyspeptic syndromes and the level of anxiety in children with these diseases. The clinical and anamnestic method was used to study the features of the clinical course of FGID accompanied by abdominal pain in children. The SCARED scale was used to determine the potential risks of development and the presence of emotional disorders associated with anxiety. Conclusions. The obtained data revealed the heterogeneity of the clinical picture in functional dyspepsia and irritable bowel syndrome in children under martial law, an increased level of anxiety, which should determine the treatment tactics for such patients.

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Bibliography:

1. Volosovets OP, Кryuchko TO, Marushko YuV, Shadrin OН, Volosovets TM, Pochynok TV, et al. Pathomorphosis of diseases of the digestive system allergic and non-allergic genesis in children of Ukraine in the dynamics of 25 years of observation. World of medicine and biology. 2022;3(81):40-45. DOI: 10.26724/2079-8334-2022-3-81-40-45.
2.  Antypkin YuH, Volosovets OP, Maidannyk VH, Berezenko VS, Moiseienko RO, Vyhovska OV, ta in. Stan zdorovia dytiachoho naselennia – maibutnie krainy (chastyna 1). Zdorovia dytyny. 2018;13(1):1-11. DOI: 10.22141/2224-0551.13.1.2018.127059. [in Ukrainian].
3. Nedielska SM, Samokhin IV, Kriazhev OV, Yartseva DO, Bessikalo TKh, Kliatska LI. Funktsionalni rozlady shlunkovo-kyshkovoho traktu u ditei riznykh vikovykh hrup (ohliad literatury). Zaporizkyi medychnyi zhurnal. 2024;26(1):66-71. Dostupno: http://zmj.zsmu.edu.ua/article/ view/290950. [in Ukrainian].
4. Bielousova OIu, Zimnytska TV, Kazarian LV. Otsinka yakosti zhyttia v ditei iz poiednanniam funktsionalnoi dyspepsii ta syndromu podraznenoho kyshechnyka. Suchasna pediatriia. Ukraina. 2023;1(129):23-27. DOI: 10.15574/SP.2023.129.23. [in Ukrainian].
5. Drossman DA. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. Gastroenterology. 2016;150:1262-1279. DOI: 10.1053/j.gastro.2016.02.032.
6. Maidannyk VH. Funktsionalni hastrointestynalni rozlady v ditei: shcho novoho? Medychna hazeta «Zdorovia Ukrainy». 2016;17(390):52- 55. [in Ukrainian].
7. Shadrin OH, Marushko TL, Niankovska OS, Bondarenko NIu. Alhorytm diahnostyky y likuvannia funktsionalnykh hastrointestynalnykh rozladiv u ditei rannoho viku. Zdorovia dytyny. 2019;14(8):52-58. [in Ukrainian].
8. Labanski A, Langhorst J, Engler H, Elsenbruch S. Stress and the brain-gut axis in functional and chronic-inflammatory gastrointestinal diseases: A transdisciplinary challenge. Psychoneuroendocrinology. 2020;111:104501. DOI: 10.1016/j.psyneuen.2019.104501.
9. Volosovets OP, Bolbot YK, Volosovets AO, Trachuk LE, Kryvopustov SP, Beketova GV, et al. Dynamics of incidence of mental and behavior disorders in children of Ukraine: a 25-years’ observation experience. Med. perspekt.. 2020;25(2):48-54. Available from: https://journals. uran.ua/index.php/2307-0404/article/view/206352.
10. Sliusar NA, Volosovets OP, Kryvopustov SP, Saltanova SD. Vplyv neirotransmiteriv na perebih funktsionalnykh hastrointestynalnykh rozladiv, asotsiiovanykh z porushenniamy emotsiino-volovoi sfery, shcho obumovleni stresom, u ditei. Zdorovia dytyny. 2024;19(4):219- 229. DOI: 10.22141/2224-0551.19.4.2024.1709. [in Ukrainian].
11. Khaustova OO, Avramenko OM. Stres ta tryvoha: psykhosomatychnyi pidkhid do terapii. Ukrainskyi medychnyi chasopys. 2023;5(157):3- 5. DOI: 10.32471/umj.1680-3051.157.248382. [in Ukrainian].
12. Bielousova OIu, Kazarian LV. Funktsionalna dyspepsiia u ditei. Problemy ta perspektyvy symptomatychnoi terapii. Zdorovia dytyny. 2021;14(8):475-479. DOI: 10.22141/2224- 0551.14.8.2019.190841. [in Ukrainian].
13. Zubarenko AV, Luzan VV, Kravchenko TY, Kopiyka GK, Martyuk VI. Psykholohichni osoblyvosti ditei z syndromom podraznenoho kyshechnyka. Aktualni problemy suchasnoi medytsyny: Visnyk Ukrainskoi medychnoi stomatolohichnoi akademii. 2020;20(1):91-95. DOI: 10.31718/2077-1096.20.1.91. [in Ukrainian].
14. Semen MO, Lychkovska OL. Riven osobystisnoi tryvozhnosti ta somatyzatsii u ditei z syndromom podraznenoho kyshechnyka. Zdorovia dytyny. 2023;18(1):53-59. DOI: 10.22141/2224-0551.18.1.2023.1559. [in Ukrainian].
15. Karulina YuV. Klinichni proiavy motornoi funktsii verkhnikh viddiliv shlunkovo-kyshkovoho traktu u ditei z vehetatyvnoiu dysfunktsiieiu. Zdorovia dytyny. 2021;15(5):302-308. DOI: 10.22141/2224¬0551.15.5. 2020.211439. [in Ukrainian].
16. Beketova HV, Volosovets OP, Horiacheva IP, Soldatova OV, Nazar OV. Etychni standarty v pediatrii: khto takyi «khoroshyi pediatr»? Zdorovia dytyny. 2023;18(4):305-311. DOI: 10.22141/2224-0551.18.4.2023.1604. [in Ukrainian].
17. Volosovets ОP, Kryuchko TO, Chernyshova OE, Volosovets AО, Trachuk LE,. Guryev SO, et al. Changes in the morbidity and prevalence of mental and behavioral disorders of children living in the warzone in eastern Ukraine. World of medicine and biology. 2021;2(76):12-17. DOI: 10.26724/2079-8334-2021-2-76-12-17.
18. Volosovets OP, Vyhovska OV, Kryvopustov SP, Mozyrska OV, Yemets OV, Volosovets AО, et al. Problems of providing medical care to children of Ukraine as a result of russian aggression. Child`s Health. 2023;18(3):157-161 DOI: 10.22141/2224-0551.18.3.2023.1578.
19. Chaban OS, Khaustova OO. Medyko-psykholohichni naslidky dystresu viiny v Ukraini: shcho my ochikuiemo ta shcho potribno vrakhovuvaty pry nadanni medychnoi dopomohy? Ukrainskyi medychnyi chasopys. 2022;4(150):1-11. DOI: 10.32471/umj.1680-3051.150.232297. [in Ukrainian].
20. Volosovets OP, Lurin IA, Naumenko OM, Volosovets AO, Kryvopustov SP. Current challenges for the health care system due to the lack of medical staff and the continuous professional development of doctors. Wiadomości Lekarskie. 2022;LXXV(5):1135-1138. DOI: 10.36740/ WLek202205115.
21. Marushko TV, Kozachuk VH, Taranenko TV, Smulska NIe. Syndrom pidvyshchenoi tryvohy yak faktor porushennia povedinky ta samopochuttia dytyny pid chas voiennoho stanu. Zdorovya Ukrayini 21 storichchya. 2024;4(565):48-49. [in Ukrainian].
22. Antypkin YuH, Volosovets OP, Lapshyn VF, Marushko RV, Dudina OO. Sytuatsiinyi analiz pervynnoi medychnoi dopomohy ditiam Ukrainy. Zdorovia dytyny. 2020;15(6):399-408. DOI: 10.22141/2224-0551.15.6.2020. 215525. [in Ukrainian].
23. Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, Tilburg M. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology. 2016;150(6):1456-68. DOI: 10.1053/j.gastro.2016. 02.015.
24. Stanghellini V, Chan FKL, Hasler WL, Malagelada JR, Suzuki H, Tack J, et al. Gastroduodenal Disorders. Gastroenterology. 2016;150:1380- 1392. DOI: https://doi.org/10.1053/j.gastro.2016.02.011.
25. Ministerstvo okhorony zdorovia Ukrainy. Nakaz Ministerstva okhorony zdorovia Ukrainy № 1122 Metodychni rekomendatsii shchodo znebolennia postrazhdalykh na etapakh evakuatsii. Kyyiv: MOZ Ukrainy; 2022. 17 s. [in Ukrainian].

Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 3, 174, 374-385 pages, index UDC 616.33/.34-002-008.6-091.1:616.8-009.7]-053.2]](477)"364"

DOI:

10.29254/2077-4214-2024-3-174-374-385