Holovko T. V., Latsynska S. A., Dyklenko T.V., Ostanina T. H., Voronkova O. S.

MICROBIOLOGY

Scentific article

Bacteriuria is quite common during pregnancy and can provoke a number of complications. If asymptomatic or symptomatic bacteriuria is detected, treatment should be given to prevent the problem from progressing and to avoid lesions for the pregnant woman and the fetus. The aim of the research was to investigate the features of the bacterial spectrum of urine in pregnant women and amniotic fluid. Routine bacteriological methods were used to isolate and determine the species of microorganisms. Analysis of urine of pregnant women revealed that 71 (13.1%) of them had symptomatic bacteriuria and 41 (7.6%) – asymptomatic. An analysis of clinical data in the case histories of women with bacteriuria shown dysuretic symptoms: pain when urinating, burning, discomfort, fever, as well as changes in the general analysis of urine (pyuria). The predominant causative agent of bacteriuria in pregnant women was E. coli – 36 (32.1%) cases. E. faecalis was also detected with a significant frequency – 31 (27.7%) cases and slightly less S. haemolyticus – 18 (16.1%) cases. Gram-positive cocci predominated in amniotic fluid: S. haemolyticus – 11 (33.3%) and E. faecalis– 10 (30.3%) cases, S. epidermidis – 3 (9.1%) cases. In some cases were isolated E. coli – 4 (12.1%) and C. albicans– 3 (9.1%). It should be noted that not necessarily the dominant microorganisms in the urine of pregnant women were found in amniotic fluid. No pathogenic microorganisms were detected in any of the studied samples of biological material. However, this does not reduce the risks and can provoke negative consequences for pregnancy. Asymptomatic bacteriuria in pregnant women can cause intrauterine infection, which threatens abortion, attachment abnormalities and premature placental abruption. Maternity and childhood protection has always been, is and will be one of the priority areas of medicine. The study of the composition of the microbiota of pregnant women and the timely detection of conditions threatening the normal delivery of pregnancy is the key to the health of women and children. Therefore, periodic monitoring studies of the composition of the microbiota of pregnant women are necessary to establish the hidden risks in order to develop and apply rational therapeutic approaches in advance.

bacteriuria, pregnancy, opportunistic microorganisms, urine, amniotic fluid.

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«Bulletin of problems biology and medicine» Issue 4 (162), 2021 year, 243-246 pages, index UDK 579.864:616.1

10.29254/2077-4214-2021-4-162-243-246