Voitiv Y. Yu., Sorokin B. V., Savoliuk S. I., Reiti A. O., Tkachuk O. V., Tyselskyi V. V.

RISK FACTORS FOR THE NEGATIVE COURSE OF GASTRODUODENAL GASTROINTESTINAL BLEEDING IN OBESE PATIENTS

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About the author:

Voitiv Y. Yu., Sorokin B. V., Savoliuk S. I., Reiti A. O., Tkachuk O. V., Tyselskyi V. V.

Heading:

CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

Annotation:

Obesity affects 25% of adults in Ukraine, which is one of the highest rates on the European continent. Treating gastrointestinal ulcer bleeding in obese patients is challenging due to 75% of them are taking at list one ulcerogenic or blood-thinning medications, and 25% use three or more because comorbidities. The problem of treating and predicting the outcomes of ulcerative bleeding in such patients is insufficiently studied. This study aimed to assess treatment outcomes for acute ulcerative bleeding in sever obese patients, evaluate the effects of age and medication use, and compare these with outcomes in normal-weight patients. In obese patients under the age of 40, ulcerative gastrointestinal bleeding associated with the use of oral anti-inflammatory drugs or medications affecting blood rheology or coagulation is a risk factor for a fatal outcome compared to patients of normal weight (7.3% and 2.1%, respectively, p- 0.2864). The incidence of early recurrent bleeding does not differ across age groups. The use of non-steroidal anti-inflammatory drugs, oral anticoagulants, and antiplatelet agents is not a risk factor and does not increase the incidence of early recurrent bleeding.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 4, 175, 282-288 pages, index UDC 616.3-05-056.527-089.15

DOI:

10.29254/2077-4214-2024-4-175-282-288