Publication of the article:
«Bulletin of problems biology and medicine», 2022 Issue 3, 166,
REGIONAL ANESTHESIA AS A TOOL FOR PREVENTION OF CHRONIC PAIN SYNDROME IN CHILDREN AFTER ANTERIOR ABDOMINAL WALL SURGERY
About the author:
Semkovych Ya. V.
Heading:
CLINICAL AND EXPERIMENTAL MEDICINE
Type of article:
Scentific article
Annotation:
The lack of adequate assessment of childhood-onset acute pain and its proper management can result in negative consequences that continue into adulthood, including chronic pain and suffering. In pediatrics, regional anesthesia (RA) is one of the most valuable and safest means of perioperative pain management, chronic pain syndrome prevention and is an essential part of modern anesthetic practice. The aim of this study was to assess the prevalence of chronic postsurgical pain in children three and six months after anterior abdominal wall surgery and the application of various approaches to anesthesia for its prevention. Object and Research Methods. The study was conducted at a Communal Non-Profit Enterprise “Ivano-Frankivsk Regional Children’s Clinical Hospital of Ivano-Frankivsk Regional Council”. There were observed 60 (35 girls, 25 boys) children at the age of 7-18 years, who underwent treatment after anterior abdominal wall surgery at the surgicaldepartment. All children were divided into two groups: Group I comprised 30 children who underwent surgery under general anesthesia using the transversalis fascia plane block (TFPB) combined with the quadratus lumborum block (QLB) via a single intramuscular injection; Group II included 30 children who underwent surgery under general anesthesia using opioids. Results and Discussion. The prevalence of chronic pain syndrome in children of Group I and Group II was found to be 9.24±0.35% and 19.81±0.21%, respectively, with a male predominance. The analysis of the length of hospital stay in the surgical department revealed that children of Group II stayed at the hospital much longer as compared to those in Group I (3.28±0.24 days in Group II vs 2.1±0.16 days in Group I, respectively, р<0.05). In children of Group II, the indicators of scales for assessing acute pain, the FLACC and VAS scores, were significantly higher as compared to those in Group I. However, on the second and third days of hospital stay, pain intensity was higher in Group II (FLACC – 4.52±0.14 and 4.0±0.16, VAS – 4.48±0.16 and 3.95±0.11, respectively) as compared to Group I (FLACC – 3.91±0.28 and 3.22±0.22, VAS – 3.58±0.28 and 3.2±0.36, respectively). Conclusions. The use of RA techniques reduces the risk of chronic pain development in children as compared to conventional anesthesia management. The advantages of the transversalis fascia plane block combined with the quadratus lumborum block (QLB+TFPB) via a single intramuscular injection are as follows: ease of use; adequate pain control; reducing perioperative use of opioid analgesics and nonsteroidal anti-inflammatory drugs; shortening the length of hospital stay.
Tags:
regional anesthesia,chronic pain,children.
Bibliography:
- 1. Eccleston C, Fisher E, Howard RF, Slater R, Forgeron P, Palermo TM, et al. Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission. Lancet Child Adolesc Health. 2021;5(1):47-87.
- Groenewald CB, Rabbitts JA, Schroeder DR, Harrison TE. Prevalence of moderate-severe pain in hospitalized children. Paediatr Anaesth. 2012;22:661-8.
- Rabbitts JA, Fisher E, Rosenbloom BN, Palermo TM. Prevalence and predictors of chronic postsurgical pain in children: a systematic review and meta-analysis. The Journal of Pain. 2017;18(6):605-614. DOI: 10.1016/j. jpain.2017.03.007.
- Williams G, Howard RF, Liossi C. Persistent postsurgical pain in children and young people: prediction, prevention, and management. Pain Rep. 2017;2(5):e616.
- Schug SA, Lavand’Homme P, Barke A, Korwisi B, Rief W, Treede R, et al. The IASP classification of chronic pain for ICD-11: chronic postsurgical or posttraumatic pain. Pain. 2019;160(1):45-52.
- Batoz H, Semjen F, Bordes-Demolis M, Bénard A, Nouette-Gaulain K. Chronic postsurgical pain in children: prevalence and risk factors. A prospective observational study. Br J Anaesth. 2016;117:489-96. DOI: 10.1093/bja/aew260.
- Rosenbloom BN, Pagé MG, Isaac L, Campbell F, Stinson JN, Wright JG, et al. Pediatric chronic postsurgical pain and functional disability: a prospective study of risk factors up to one year after major surgery. J Pain Res. 2019;12:3079-98. DOI: 10.2147/JPR.S210594.
- Kristensen AD, Ahlburg P, Lauridsen MC, Jensen TS, Nikolajsen L. Chronic pain after inguinal hernia repair in children. British Journal of Anaesthesia. 2012;109(4):603-608. DOI: 10.1093/bja/aes250.
- Mossetti V, Boretsky K, Astuto M, Locatelli BG, Zurakowski D, Lio R, et al. Persistent pain following common outpatient surgeries in children: a multicenter study in Italy. Paediatr Anaesth. 2018;28(3):231-6.
- Aasvang EK, Kehlet H. Chronic pain after childhood groin hernia repair. Journal of Pediatric Surgery. 2007;42(8):1403-1408. DOI: 10.1016/j. jpedsurg.2007.03.042.
- Hernia Surge Group. International guidelines for groin hernia management. Hernia. 2018;22(1):1-165. DOI: 10.1007/s10029-017-1668-x.
- Martin J. Regional anaesthesia in neonates, infants and children: An educational review. Eur J Anaesth. 2015;32:289-97.
- Marella F. General principles of regional anesthesia in children. BJA. 2019;9:342-348.
- Baidya DK, Maitra S, Arora MK, Agarwal A. Quadratus lumborum block: an effective method of perioperative analgesia in children undergoing pyeloplasty. J Clin Anesth. 2015;27:694-696.
- Blanco R. Tap block under ultrasound guidance: the description of a “no pops” technique. Region Anesth Pain Med. 2007;32:S1-130.
- Chakraborty A, Goswami J, Patro V. Ultrasound-guided continuous quadratus lumborum block for postoperative analgesia in a pediatric patient. A Case Rep 2015;4:34-6.
- Вlanco R, Ansari T, Girgis E. Quadratus lumborum block for post-operative pain after caesarean section: a randomised controlled trial. Eur J Anaesthesiol. 2015;32:812-8.
- Blanco R, Ansari T, Riad W, Shetty N. Quadratus lumborum blockversus transversus abdominis plane block for postoperative painafter cesarean delivery: a randomized controlled trial. Reg Anesth Pain Med. 2016;41:757-62.
- Ueshima H, Otake H, Lin JA. Ultrasound-guided quadratus lumborum block: an updated review of anatomy and techniques. Biomed Res Int. 2017;2017:275-287.
- Dam M, Moriggl B, Hansen CK, Hoermann R, Bendtsen TF,Børglum J. The pathway of injectate spread with the transmuscularquadratus lumborum block: a cadaver study. Anesth Analg. 2017;125:303-12.
- Elsharkawy H, Ahuja S, DeGrande S, Maheshwari K, Chan V. Subcostal approach to anterior quadratus lumborum block for pain control following open urological procedures. J. Anesth. 2019;33:148-154.
- Ahiskalioglua A, Aydina ME, Doymusa O, Yayikb AM, Celikb EC. Ultrasound guided transversalis fascia plane block for lower abdominal surgery: First pediatric report. Journal of Clinical Anesthesia. 2019;55:130-131. DOI: https://doi.org/10.1016/j.jclinane.2018.12.046.
- World Health Organization. International Classification of Diseases 11th Revision [Internet]. Geneva: World Health Organization; 2019. Available from: https://icd.who.int/en.
- King S, Chambers CT, Huguet A, MacNevin RC, McGrath PJ, Parker L, et al. The epidemiology of chronic pain in children and adolescents revisited: a systematic review. Pain. 2011;152(12):2729-2738.
- Schug S, Bruce J. Risk stratification for development of chronic post-surgical pain. Pain Reviews. 2017;2:e627.
- Walco GA, Cassidy RC, Schechter NL. Pain, hurt, and harm. The ethics of pain control in infants and children. N Engl J Med. 1994 Aug 25;331(8):541-4.
- McBain R, Rose AJ, LaRochelle MR. The U.S. opioid epidemic: one disease, diverging tales. Prev Med. 2018;112:176-8.
- Grace PM, Strand KA, Galer EL, Urban DJ, Wang X, Baratta MV, et al. Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation. Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):E3441-50.
- Wiegele M, Marhofer P, Lönnqvist P-A. Caudal epidural blocks in paediatric patients: a review and practical considerations. Br J Anaesth 2019;122:509-17.
Publication of the article:
«Bulletin of problems biology and medicine» Issue 3 (166), 2022 year, 236-245 pages, index UDK 615.211+616-071.4+616-085+613.95+617.55
DOI:
10.29254/2077-4214-2022-3-166-236-245