Leush S. S.

PONDUS HYDROGENII (pH) OF MOTHERS AND NEWBORNS BLOOD BY DIFFERENT CONDITIONS AND TERMS OF DELIVERY

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About the author:

Leush S. S.

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CLINICAL AND EXPERIMENTAL MEDICINE

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Scientific article

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The removal of fetal metabolites occurs into the more alkaline maternal blood. The mechanisms of the increase in maternal blood pH in pregnancy have not been fully elucidated. The aim of the study was to determine the permissible deviations of the acid-base balance of maternal and fetal blood and their consequences in different conditions of pregnancy and delivery. The indices of acid-base balance of maternal venous blood in the second stage of the first labor and newborns umbilical arterial blood were studied in four groups: extremely preterm labor - 16 women in labor with a term of 24-27 weeks, moderate preterm birth - 36 women at 28-34 weeks, fetal growth restriction group - 26 women at 28-34 weeks, control - 24 full-term women in labor. All women aged 18-35 years with a single occipital delivery, normal cardiotocography, without induction or tocolysis. The mother's pH increases with gestational age. The maternal vs fetal pH difference was 0.03-0.07 in the case of preterm birth, 0.10 in fetal retardation and 0.13 in full-term births. Conclusions. 1. The umbilical artery pH is highest in extremely premature newborns. Newborns with growth retardation have the lowest pH levels. 2. The difference between the pH values of maternal venous blood and the umbilical arterial blood is smaller in the case of premature birth. In the case of growth retardation, the pH difference is close similar to full-term ones. There is a relatively low maternal venous blood pH in such cases.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 3, 174, 157-166 pages, index UDC 618.39-06:618.38-008.82:612.121:612.127

DOI:

10.29254/2077-4214-2024-3-174-157-166