Zvir M. Y., Pohoretska Ya. O., Zayachkivska O. S.

PHYSIOLOGY

Scentific article

An actual problem of modern medicine is to increase the spread of diseases related to life style, it is known that specific physiological processes in the body are closely dependent on physical activity, behavior, synchronization of circadian rhythms with regular meals, adequate environment, social climate, and the like. An important resource for early diagnosis of many diseases and functional condition of the body in recent years is saliva. Normal saliva is necessary to moisten the mucous membrane of the upper gastrointestinal tract, the composition of saliva includes many factors that ensure normal function and protect the whole body – epidermal growth factor responsible for physiological regeneration, forming mucin in mucous-bicarbonate barrier, specific and nonspecific bioprotection that play critical role in the integrity of the gastrointestinal epithelial barrier and overall resistance to extreme factors. The aim – to study the effect of risk factors, micro-factors, emotional state of individual characteristic physiological responses and assess the state of saliva microcrystallization in students. Estimation of saliva samples was provided by two independent investigators. The determination of microcrystallization type was carried out due to the classification of Havrylyuk N.S. (2012), Shatohina S.N. (2006): type 1 – clear equably disposed crystal prismatic structures connected with each other in appearance of fern leaf; type 2 – separate small tree like crystals or polyformed solitary crystals in appearance of net equably disposed through vision field; type 3 – irregular formed structures in isometrical disposition; type 4 – absence of crystals. The part of left saliva was taken for further investigations. Statistical analysis was carried out by Mean calculating (Mean) and their standard deviations (SD) (Mean±SD). The difference between means was estimating by Mann-Whitney U-criterion. Statistical software Statistica 10.0 (Statsoft, Tulsa, Oklahoma, USA) was used for all data. The study was conducted among 70 students of Lviv national medical University named Danylo Galytsky, collected general information about the participants, established risk factors of lifestyle related with physical activity, estimated cercadian rhythm, use of modern gadgets and the presence of functional gastrointestinal disorders. The assessment of saliva secretion and the state of its microcrystallization.The results of the study showed that 70% of students have reduced daily duration of skeletal muscle contractility, expressed circadian dysfunction and excessive usage of gadgets that lead to changes in secretion of saliva and microcrystallization of nutrients that indicate the imbalance of the autonomic nervous system. About 30% of the participants had signs of functional disorders of the upper digestive tract. Thus, the results of saliva microcrystallization are a prerequisite for the further investigation as an effective diagnostic tool for detecting early changes in the body. Prospects for further research. Integrative look at changes saliva microcrystallization could be a new diagnostic tool for the early detection of health disorders. Maintaining regular activity of skeletal muscles and compliance with the normal circadian rhythm is physiological promising approach of improving the health of young people.

saliva, scrollsize, microscopy, physical activist, circadian rhythm

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«Bulletin of problems biology and medicine» Issue 1 (135), 2017 year, 407-411 pages, index UDK 616.316-008.8-076.4-057.87