Vashcheniuk M. I.

MORPHOLOGY OF THE DORSOMEDIAL AND VENTRAL HYPOTHALAMIC NUCLEI

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About the author:

Vashcheniuk M. I.

Heading:

MORPHOLOGY

Type of article:

Scientific article

Annotation:

The hypothalamus is a part of the diencephalon that secretes hormones and neuropeptides and is responsible for homeostasis, hunger, thirst, behavioural reactions, and even sleep. The anatomy of the hypothalamus in normal and pathological conditions is widely described in the literature. However, there is little information on the normal histological structure of the tuber cinereum of the hypothalamus, not to mention the description of changes under the influence of pathological factors. It is the understanding of the macro- and microstructure of this area that makes it possible to investigate and analyse the results of experimental studies under the influence of exogenous and endogenous factors in laboratory animals. A specific structural area was chosen for a more effective analysis of the experiment: the dorsomedial and ventral nucleus. The work aims to create a set of morphological and morphometric parameters of the tuber cinereum of the hypothalamus of the white rat, which is necessary for further analysis of structural changes in this organ in pathological conditions in the experiment. The material of the study is represented by macro- and microdissections of the tuber cinereum of the hypothalamus of 10 male white rats of the Wistar line weighing 218-260 g. Measurements of the size of the tuber cinereum of the hypothalamus were performed using a caliper, weighing – on an analytical balance. Histological sections were stained with haematoxylin and eosin, after which the microscopic structure of the tuber cinereum of the hypothalamus was studied. The topography and peculiarities of cytoarchitectonics of the tuber cinereum were described, and the dorsomedial and ventromedial nuclei of the hypothalamus were micromorphologically characterised. The morphological and morphometric parameters of the tuber cinereum of the white rat hypothalamus can serve as a basis for experimental studies and understanding of the mechanisms of development of changes in the structural components of this organ.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2023 Issue 4, 171, 316-322 pages, index UDC 611.814.1

DOI:

10.29254/2077-4214-2023-4-171-316-322