Oleksiienko V. V., Bilash S. M.

MORPHOLOGICAL CHANGES IN THE ARTERIOLES OF THE HAEMOMICROCIRCULATORY BED OF THE GINGIVAL MUCOSA UNDER PROLONGED EXPOSURE TO FOOD ADDITIVES

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About the author:

Oleksiienko V. V., Bilash S. M.

Heading:

MORPHOLOGY

Type of article:

Scientific article

Annotation:

Nowadays, food additives are an important element of the food industry, which not only improve the taste of products, but also allow them to be stored longer. At the same time, they have negative properties that manifest themselves after long-term use. The experiment was aimed at identifying the effect of several food additives on the gums, vessels and changes in their structure. During the study, it was established that the effect of a complex of food additives (sodium glutamate, sodium nitrite, and Ponceau 4R) on the microvessels of the gums of rats leads to a violation of hemodynamic conditions, and with prolonged action leads to an irreversible violation of blood supply to the gums as a whole. Morphological changes of microvessels (first of all arterioles) are observed mainly from the fourth week of the experiment and are characterized by vasodilatation or vasoconstriction, the formation of erythrocyte aggregates, which leads to significant pathological changes in the structural organization of the gums and blood supply to the gums, as an integral organ of the oral cavity.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2023 Issue 3, 170, 412-416 pages, index UDC 616.311.2: 615.241

DOI:

10.29254/2077-4214-2023-3-170-412-416