Shatorna V. F., Zaparia O. O., Stryzhak O. V.

MODERN PERSPECTIVE ON THE PREVALENCE AND DEVELOPMENT OF DISEASES UNDER THE INFLUENCE OF CHLAMYDIA TRACHOMATIS (A LITERATURE REVIEW)

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About the author:

Shatorna V. F., Zaparia O. O., Stryzhak O. V.

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LITERATURE REVIEWS

Type of article:

Scientific article

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Chlamydial infections constitute a group of infectious diseases of anthropozoonotic and zoonotic origin, which are responsible for a wide range of diverse pathologies in more than half a billion people worldwide. According to the World Health Organization (WHO), urogenital chlamydia is the second most prevalent sexually transmitted disease (STD) after trichomoniasis. It is estimated that over 90 million new cases of Chlamydia trachomatis infection occur annually worldwide, resulting in economic losses amounting to billions of dollars. Ukraine is no exception to this trend, with thousands of new cases of diseases caused by this type of chlamydia registered annually in hospitals and laboratories. However, many cases remain undiagnosed due to incomplete diagnostics, the variety of target sites affected in the human body, or the long incubation period. Chlamydia trachomatis is an obligate intracellular, gram-negative, immobile bacterium that is the causative agent of trachoma, sexually transmitted diseases, certain forms of arthritis, conjunctivitis, and pneumonia in newborns. Furthermore, infection with Chlamydia trachomatis increases the risk of HIV infection due to the weakened immunity of the patient. The aim of this study was to search and analyse existing literature on the bacterium's life cycle, transmission routes, the impact of Chlamydia trachomatis infection on the human body, and prevention methods. A review of current medical and biological scientific publications revealed that the morphogenesis of Chlamydia trachomatis and its impact on the human body, particularly in chronic disease forms, remain insufficiently studied and require further research, including interdisciplinary approaches. Furthermore, the number of individuals infected with this microorganism is increasing, underscoring the necessity for educational initiatives among the general population, particularly in high-risk groups.

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Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 4, 175, 161-169 pages, index UDC 616.61:591.3:546.48:612.6

DOI:

10.29254/2077-4214-2024-4-175-161-169