One of important problems of modern biology and medicine is the individualization of the adaptation (protocoale) reactions to different stimuli, pathological conditions, diseases, etc. Therefore study the level of adaptive tension and related cell reactivity 7-10 year-old children with visual impairments to the definition of health status and forecasts the possible rehabilitation of the physical development of these children, determines the relevance of the study. The purpose of the study is to establish the level of adaptive tension and cell reactivity of children aged 7-10 years with visual impairments. A laboratory examination of peripheral blood in children aged 7-10 years, enrolled in a secondary school № 17 Slavyansk, Donetsk region specialized boarding school № 23 for the blind and visually impaired children. A group of children (31 children), that he studied at the Slavic specialized secondary boarding school I-III stages № 23 and consisted of 14 boys and 17 girls. To establish the level of adaptive tension and cell reactivity of children used standalone Hematology analyzer N. In. For the study, the children were taken from lacto vein whole blood, it smushes in a clean test tube anticoagulants that preserves the structure of the lymphocytes, leukocytes, monocytes, macrophages and red blood cells and prevents the accumulation of platelets. The process of counting the absolute and relative amounts of the major populations of immune cells was carried out according to the instruction manual for auto Hematology analyzer mseries. The obtained results were processed using software programs MUSTAT.12 (USA). In children aged 7-10 years with visual impairments are formed upward trend in absolute and relative amount of IKK involved in the implementation of non-specific immune defense, as well as to growth in the absolute number of lymphocytes and decrease in relative number of lymphocytes and monocytes erythrocyte sedimentation ratein children with visual impairments and in healthy children is in the area of the normal type, but the current upward trend in erythrocyte sedimentation rate in children with visual impairments. When studying the absolute and relative number of major populations of IKK in peripheral blood of boys aged 7-10 years with visual impairments a trend to increase, indicating activation of factors and mechanisms of nonspecific reactivity of the organism, and the factors and mechanisms specific acquired immune reactivity lags behind indicators in healthy boys aged 7-10 years. Girls aged 7-10 years with vision pathology absolute and relative number of major populations of IKK in peripheral blood in comparison with that of healthy girls, the trend to an increase in the absolute number of leukocytes, by increasing the concentration of granulocytes by 14.48%, including neutrophils of granulocytes at the expense of Mature forms. Study of the effect of a pathology of sight at children aged 7-10 years at the level of adaptive tension of the organism, parameters of cellular reactivity in children (boys and girls) aged 7-10 years with visual impairments adaptation index is in the area of the body’s response to training with a minor (by 4.55%) advantage of girls. According to the results of established cell reactivity 7-10 year-old children with visual impairments increases the level of cellular reactivity, which is confirmed by increased levels of hematological index of intoxication by V. S. Vassilev, the improvement of which is associated with a decrease or increase of other leukocyte indexes of intoxication. The level of cellular reactivity in children 7-10 years with visual impairments depend on gender. Cellular reactivity in girls are higher than boys that age. The level of intoxication in girls, to a greater extent evident infectious process, in boys with visual impairments – intoxication caused by autoimmune processes. Obtained and presented in the article the basic scientific principles is the basis for the study of the impact of measures and means aimed at improving the adaptation processes of cell reactivity of children with visual impairments.
«Bulletin of problems biology and medicine» Issue 1 (135), 2017 year, 391-397 pages, index UDK 612.017-056.262:796
