Lisova G. V., Makovozov O. O.

FEATURES OF PERIOPERATIVE COMPLICATIONS OF SURGICAL TREATMENT OF PATIENTS WITH INTRAVENOUS SPREAD OF RENAL CELL CARCINOMA

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About the author:

Lisova G. V., Makovozov O. O.

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CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

Annotation:

Difficult situations in the surgery of tumor thrombi of the inferior vena cava are very common, since this surgical intervention is characterized by significant technical problems and severe perioperative complications. The most dangerous of them include massive bleeding, acute heart failure and pulmonary embolism with tumor masses, heart and kidney failure. It is these problems that are most often the causes of perioperative mortality. It is believed that many factors influence the complication rate. In our study, which included 124 patients (53 of them with III (n=27) and IV (n=26) levels of intraluminal tumors), intra- and postoperative mortality was 2.4% and 4.0%, respectively. Mortality was recorded only in patients with retro hepatic or supradiaphragmatic thrombi. Among our patients, the most common complications were renal failure, heart failure, and IVC blood thrombosis, with a severe complication rate of up to 25%. Radical nephrectomy with vena cava thrombectomy is a complex surgical intervention, which is accompanied by a high level of intra- and postoperative complications. The frequency of complications significantly depends on the level of spread of the intracaval tumor. This surgical operation requires the modernization of the surgical technique for the removal of retro hepatic and supradiaphragmatic thrombi. The improvement of methods for assessing its complexity and predicting severe complications is also needed.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2023 Issue 2, 169, 263-268 pages, index UDC 616.61–006.6:616-08:617-089

DOI:

10.29254/2077-4214-2023-2-169-263-268