Baibakov V. M., Ostrovska S. S., Rodionov V. K., Khomyakov V. M., Guzenko B. V., Kryzhanovsky I. D., Vlasova K. R.

EXPERIMENTAL MODELING OF NEGATIVE CONSEQUENCES OF GENERALLY ACCEPTED METHODS OF SURGICAL INTERVENTION ON ELEMENTS OF THE SPERM CORD

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About the author:

Baibakov V. M., Ostrovska S. S., Rodionov V. K., Khomyakov V. M., Guzenko B. V., Kryzhanovsky I. D., Vlasova K. R.

Heading:

METHODS AND METHODOLOGIES

Type of article:

Scientific article

Annotation:

In the experimental work on rats, a morpho-functional model of the negative effects of the conventional surgical technique on the elements of the spermatic cord in the inguinal-scrotal region with a complete circular crossing of the vaginal process of the spermatic cord was created. The inguinal canal was completely dissected along its entire length, the spermatic cord was taken on a surgical turnstile, and the vaginal process of the spermatic cord was cir cularly crossed at three levels: directly above the testis, in the middle third of the spermatic cord, and at the level of the deep inguinal ring. The experimental animals were withdrawn from the experiment on days 1, 15, and 30. The material was studied by histological examination, the results of which showed the dynamics of pathomorphological changes in the inguinal-scrotal region during surgery according to the generally accepted surgical technique. After experimental modeling of the pathological process, all experimental animals had significant disorders of testicular circulation with the development of acute hypoxia in the testes. Throughout the entire period of the experimental study, the development of widespread sclerotic changes in the structural elements of the spermatic cord and the testis itself was observed, which led to its gross deformation with impaired sperm evacuation and a high risk of me chanical obturative infertility. It has been shown that the preservation of the main vascular anastomoses between all elements of the spermatic cord can significantly improve testicular blood circulation in the postoperative period and significantly reduce the likelihood of developing fertility disorders in the reproductive period. The data obtained from our study clearly substantiated the need to implement minimally invasive methods of surgical correction in the inguinal-scrotal area and to develop more advanced ways of testicular regeneration in the postoperative period in surgical and urological practice.

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Bibliography:

1. Xu C, Xiang B, Jin SG. Transumbilical Two-Port Laparoscopic Percutaneus Extraperitoneal Closure: A New Technique for Inguinal Hernia Repair in Children. Journal of Laparoendoscopic Advanced Surgical Techniques, Part A. 2023;234:392-396.
2. Patkowski D, Czernik J, Chrzan R. Percutaneous Internal Ring Suturing: A Simple Minimally Invasive Technique for Inguinal Hernia Repair in Children. J. Laparoendosc. Adv. Surg. Techn. 2023;16:513-517.
3. Ron O, Eaton S, Pierro A. Systematic Review of the Risk of Developing a Metachronous Contralateral Inguinal Hernia in Children. British Journal of Surgery. 2023;94:804-811.
4.  Al-Jazaeri A, Asiri Y, Alkahtani S. Percutaneous obliteration of patent processus vaginalis: A rat model for future inguinal hernia repair in children. J. Pediatr. Surg. 2022;48:203-208.
5.  Chang YT. Technical Refinements in Single-Port Laparoscopic Surgery of Inguinal Hernia in Infants and Children. Diagnostic and Therapeutic Endoscopy. 2022;5:392847.
6.  Wang KS. Committee on Fetus and Newborn and Section on Surgery Assessment and Management of Inguinal Hernia in Infants. Pediatrics. 2022;1304:768-773.
7.  Ponsky T, Nalugo M, Ostlie DJ. Pediatric laparoscopic inguinal hernia repair: a review of the current evidence. J. Laparoendosc. Adv. Surg. Tech. 2023;24:183-187.
8.  Zallen G, Glick PL. Laparoscopic inversion and ligation inguinal hernia repair in girls. J. Laparoendosc. Adv. Surg. Tech. 2022;17:143-145.
9.  Dilek OH. Hernioplasty and testicular perfusion. Springer Plus. 2023;3:107.
10.  Coran AG, Caldamone A, Adzick NS. Inguinal hernias and hydroceles. Pediatric Surgery. 2022;76:85-1001.
11.  Ho CH, Yang SS, Tsai YC. Minilaparoscopic high-ligation with the processus vaginalis undissected and left in situ is a safe, effective, and durable treatment for pediatric hydrocele. Urology. 2022;76:134-137.
12.  Sozubir S, Ekingen G, Senel U. A continuous debate on contralateral processus vaginalis: evaluation technique and approach to patency. Hernia. 2023;10:74-78.
13.  Wang JH, Zhang W, Tou JF. Incidence of Pediatric Metachronous Contralateral Inguinal Hernia in Children Aged Year ≥. World Journal of Pediatrics. 2022;8: 256-259.
14.  Zavras N, Christou A, Misiakos E. Current Trends in the Management of Inguinal Hernia in Children. International Journal of Clinical Medicine. 2023;5:770-777.

Publication of the article:

«Bulletin of problems biology and medicine», Issue 2,177, 320-328 pages, index UDC 616.681: 616.688 - 089.843 - 008.811.9 - 092.9

DOI:

10.29254/2077-4214-2025-2-177-320-328