EFFECT OF INCREASED HOMOCYSTEINE LEVELS ON ENDOCRINE GLANDS AND ON CHANGES IN THE STRUCTURE OF THE RAT HEART

Kaminskyi R.F., Dzevulska I.V., Tymoshenko I.O., Ihnatyshchev M.R., Yanchyshyn A.Y.

EFFECT OF INCREASED HOMOCYSTEINE LEVELS ON ENDOCRINE GLANDS AND ON CHANGES IN THE STRUCTURE OF THE RAT HEART


Show/Download

About the author:

Kaminskyi R.F., Dzevulska I.V., Tymoshenko I.O., Ihnatyshchev M.R., Yanchyshyn A.Y.

Heading:

PROSPECTS FOR THE DEVELOPMENT OF MORPHOLOGICAL AND CLINICAL RESEARCH

Type of article:

Scientific article

Annotation:

In this article, we examine a fundamentally new issue in the development of cardiovascular and endocrine system diseases, which unfortunately has not been studied by various scientists in the European Union and the United States in recent years. The problem of the impact of elevated homocysteine levels has only begun to be studied in recent years, and we investigated the negative effects of hyperhomocysteinemia (HHcy) on the structure of the heart and endocrine organs. Unfortunately, this risk factor, such as hyperhomocysteinemia, tends to increase, which will further lead to increased mortality and disability rates, especially among young and working-age individuals. This problem is of serious concern as the number of vascular events, such as heart attacks and strokes, is rising, resulting in higher economic costs for the medical rehabilitation of patients after these events. The rehabilitation processes for such patients can sometimes take up to 6 months, which may impact the economic development of the country.

Tags:

endocrine glands, heart, homocysteine

Bibliography:

  1. Handziuk VA, Dyachuk DD, Kondratiuk NYu. Dynamika zakhvoryuvanosti ta smertnosti vnaslidok khvorob systemy krovoobihu v Ukraini (rehional’nyi aspekt). Visnyk Problem Biolohii i Medytsyny. 2017;2:319-323. [in Ukrainian].
  2. Ol’khovs’kyi OS, Mel’nyk AV, Zaichko NV. Vikovi vidminnosti produktsii hidrohen sul’fidu v sertsi ta aorti shchuriv. Aktual’ni Problemy Suchasnoyi Medytsyny. 2011;11(4):133-137. [in Ukrainian].
  3. Raksha N, Halenova T, Maievskyi O, Dzevulska I, Kaminsky R, Yanchyshyn A, et al. Biochemical disorders in the thyroid gland in rats with hyperhomocysteinemia. Biomedical Research and Therapy. 2022;9(5):5065-5074.
  4. Zaichko N, Lutsiuk M, Hryhorieva H. Hipergomotsysteinemia: medyko-sotsialni ta farmakolohichni aspekty. Farmatsevtychnyi Kurier. 2012;9:30-35. [in Ukrainian].
  5. Andrushko I, Pentiuk O. Morfologichni zminy v aorti ta sertsi shchuriv za umov eksperymentalnoi hipergomotsysteinemii ta korektsii yii vitaminno-mineralnym kompleksom. Bukovynskyi Medychnyi Visnyk. 2010;14(1):105-109. [in Ukrainian].
  6. Kaminsky RF, Dzevulska IV, Yanchyshyn AY, Matkivska RM, Samborska IA. Submicroscopic changes in the heart of adult rats under conditions of persistent hyperhomocysteinemia. Reports of Morphology. 2022;28(3):21-25.
  7. Kaminsky RF. Electronic-microscopic changes of the heart of old rats with hyperhomocysteinemia. Visnyk Vinnytskoho Natsionalnoho Medychnoho Universytetu. 2022;26(3):365-368.

Publication of the article:

«Bulletin of problems biology and medicine», 2024 Issue 2, 173, addition, 27-28 pages, index UDC 616.12-008.1+616.43]:577.112.34-043.2-092.9

DOI:

10.29254/2523-4110-2024-2-173/addition-27-28

Was this article helpful?

Leave a Reply

Your email address will not be published. Required fields are marked *


The reCAPTCHA verification period has expired. Please reload the page.