Poltorapavlov V. A., Bodnar V. A., Iziumska O. M., Lymarenko N. P., Syzova L. M., Marchenko O. H., Zdor O. I.
EDEMA-SWELLING OF THE BRAIN IN THE CLINIC OF INFECTIOUS DISEASES: PATHOGENESIS, CLINIC, DIAGNOSIS, TREATMENT
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Poltorapavlov V. A., Bodnar V. A., Iziumska O. M., Lymarenko N. P., Syzova L. M., Marchenko O. H., Zdor O. I.
Heading:
LITERATURE REVIEWS
Type of article:
Scientific article
Annotation:
Edema-swelling of the brain is a pathological condition caused by swelling of brain tissues with an increase in its volume and an increase in intracranial pressure. Today, questions about classification, etiological differences, the nature of "trigger mechanisms," the relationship of the processes underlying the development of edema-swelling of the brain, and efforts to differentiate edema from swelling during the treatment of the patient are still being discussed. The question of the most rational therapeutic approaches is also relevant. Therefore, it is necessary to analyze modern clinical concepts, and diagnostic and treatment strategies, presented in the literature regarding the problems of early diagnosis of cerebral edema, the significance of its clinical definition, and treatment at the prehospital and hospital stages. In the clinic of infectious diseases, edema-swelling of the brain occurs most often with inflammatory processes in the brain and meninges: with bacterial and viral meningitis, encephalitis; diseases that are accompanied by the development of cerebral vasculitis (severe forms of influenza, hemorrhagic fevers, malaria), so the correct diagnosis and treatment of this pathological syndrome is of crucial importance for the successful therapy of many infectious diseases. From the point of view of pathomorphology, edema, edema-swelling, and swelling of the brain are separate pathological processes that occur independently or simultaneously can complement and pass into each other. These conditions manifest similarly, but different treatment principles must be followed. Edema-swelling of the brain due to infectious diseases pathogenetically refers more to the cytotoxic form and requires the appointment of drugs that increase intracellular metabolism.
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Bibliography:
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Publication of the article:
«Bulletin of problems biology and medicine», 2023 Issue 2, 169, 89-100 pages, index UDC 616.831-002:616.9-071-085