Established substantial increase in the incidence of allergy intolerance of different dental materials, as manifested by specific T-cell responses of the body, mainly psevdoalerhichnymy or a combination thereof. However, dentist, choosing materials for preventive measures and restoration of teeth guided by several criteria, including: aesthetics, duration of therapy guarantees, comfort in work and price / quality ratio. Such requirements fully in the present, corresponds plastic composite light curing renhenkontrasnyy GC Gradia Direct Flo (Japan), which includes traditional resin – dymetylakrylat – BisGMA. Bisphenol A, which is part of the photopolymer fillings affects the organs and systems that are sensitive to estrogen, and – the remaining methacrylate without polymerization after photopolymerization, is toxicological danger to the patient, including allergic contact stomatitis. Especially the situation worsens if the dental patient suffers from diabetes. Therefore, it was investigated how the microvasculature structure periodontitis in rats in the presence of the seals and diabetes mellitus. The structure of periodontal tissue in rats with induced diabetes in dynamics, and when combined with the presence of this pathology photopolymer and cement fillings. Under the conditions of streptozotocin-induced diabetes occur gradually and are progressing structural changes of the microvasculature in the soft periodontal tissues. Arteriolar lumen narrowing. The walls of capillaries and arterioles will melt fat some, especially in the papillary layer. Connective tissue papillae are smoother appearance. Intraepithelial, subepithelial, in the area marked gingival crevices different infiltration, indicating acute inflammation. Small hemorrhages are marked. In the lamina propria mucosa lumen vascular microcirculation narrowed. Was marked venous plethora, dilatation lumen of the capillaries. In papillary layer arteriolar lumen is 10,9 ± 0,09 mкm, the capillaries – 6,6 ± 0,33 mкm, and venules – 21 ± 0,014 mкm. In papillary layer around blood vessels were found lymphocytes, macrophages and mast cells. In the reticular layer, visually increasing the number of macrophages and mast cells. In the presence of photopolymer filling material diabetes mellitus along with the restructuring of the microvasculature increases the number of lymphocytes in the lamina propria and the number of fat cells around the gingival pocket. In animals in which the filling material was presented against the background of a cement material diabetes changes concerning the restructuring of the microvasculature, for animals with diabetes.
«Bulletin of problems biology and medicine» Issue 2 part 1 (128), 2016 year, 364-367 pages, index UDK 611.314.1-018:612.014.462.6]-08