Letsyn D. V., Nikiforov O. A.

ANALYSIS OF THE RESULTS OF UTERINE AND OVARIAN ARTERY BLOOD FLOW DEPENDING ON THE SCHEME OF CONTROLLED OVARIAN STIMULATION

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About the author:

Letsyn D. V., Nikiforov O. A.

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CLINICAL AND EXPERIMENTAL MEDICINE

Type of article:

Scientific article

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The aim of the study was to investigate the Doppler characteristics of uterine and ovarian hemodynamics in women undergoing in vitro fertilization (IVF) depending on the controlled ovarian stimulation protocol used. A total of 110 patients who were enrolled in assisted reproductive technology programs were examined. All patients in both the main and control groups undergoing the IVF program underwent the following procedures: anthropometry with determination of the body mass index (BMI) and identification of the woman’s morphological type; biochemical analysis (determination of serum levels of antidiuretic hormone, aldosterone, prolactin, 17-hydroxyprogesterone, and androstenedione); and ultrasound examination of the uterus and ovaries with Doppler assessment of blood flow in the vessels of these organs. When standard ovulation induction protocols were applied in the IVF program, the obtained echographic parameters in both uterine arteries indicated an increase in peak velocities in the right uter ine artery in patients receiving standard ovulation induction protocols and in patients receiving combined therapy on days 2-3 of the menstrual cycle and on the day following administration of the ovulation trigger. An increase in minimum blood flow velocities in the right and left uterine arteries, along with a decrease in the systolic-to-diastolic ratio and resistance index, was observed in patients receiving standard ovulation induction protocols and in patients receiving combined therapy on the day following ovulation trigger administration compared with the values record ed on days 2–3 of the menstrual cycle in these two groups.

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Bibliography:

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Publication of the article:

«Bulletin of problems biology and medicine», 2026 Issue 1, 180, 279-287 pages, index UDC 618.11+618.14]-005.1:616.12-008.33]]-073-085

DOI:

10.29254/2077-4214-2026-1-180-279-287