Pariienko K. O. Nechaiev V. V
ANALYSIS OF THE RELATIONSHIP BETWEEN EXTRAGENITAL FACTORS AND THE DEVELOPMENT OF GENITAL PROLAPSE IN WOMEN
Show/Download
About the author:
Pariienko K. O. Nechaiev V. V
Heading:
CLINICAL AND EXPERIMENTAL MEDICINE
Type of article:
Scientific article
Annotation:
Genital prolapse continues to be a relevant gynecological issue, especially among older women. The importance of proper planning and timely execution of surgical treatment in such cases becomes particularly significant. The purpose of this study was to establish the relationship between extragenital pathology and the development of genital prolapse. A retrospective cohort study was conducted at Dnipro State Medical University, Department of Obstetrics and Gynecology, from 2012 to 2022, involving 1989 patients. Genital prolapse (GP) investigation found 4.5±0.2 concomitant extragenital pathologies, notably from intra-abdominal pressure-related conditions like lung diseases. Cardiovascular issues (hypertension 21.7%, ischemic heart disease 19.5%) were common, often with metabolic disorders. Connective tissue dysplasia (CTD) signs included foot deformities (9.1%) and hernias (8.4%). Importantly, 76.3% of GP patients had systemic CTD. This underscores GP's multifaceted nature and the importance of considering extragenital pathologies and CTD in assessment. This investigation uncovered a diverse array of extragenital pathologies in genital prolapse (GP) patients, averaging 4.5±0.2 conditions per patient. Elevated intra-abdominal pressure-related disorders, such as chronic obstructive lung diseases and allergies, stood out as significant contributors to GP. Cardiovascular issues, metabolic disorders, and connective tissue dysplasia (CTD) were also prevalent. Notably, 76.3% of GP patients displayed signs of systemic CTD, underscoring its pivotal role in GP development.
Tags:
Bibliography:
- Schulten SFM, Claas-Quax MJ, Weemhoff M, van Eijndhoven HW, van Leijsen SA, Vergeldt TF, et al. Risk factors for primary pelvic organ prolapse and prolapse recurrence: an updated systematic review and meta-analysis. Am J Obstet Gynecol. 2022 Aug;227(2):192-208. DOI: 10.1016/j.ajog.2022.04.046.
- Banakhevych R, Akymova K, Pariienko K, Nechaiev V. Transvaginal surgical treatment of stage III-IV cystocele using a light prolene mesh: Safety of use and 5-year follow-up results. Urologia. 2023 Aug;90(3):522-526. DOI: 10.1177/03915603231168011.
- Banakhevych R, Akymova K, Pariienko K, Nechaiev V. Prevention of complications of surgical treatment of stage III-IV cystocele using light polypropylene mesh. Urologia. 2023 Aug 22:3915603231193059. Epub ahead of print. DOI: 10.1177/03915603231193059.
- Chermansky CJ, Winters JC. Complications of vaginal mesh surgery. Curr Opin Urol. 2012 Jul;22(4):287-91. DOI: 10.1097/ MOU.0b013e32835480b2. PMID: 22617058.
- Januszyk M, Gurtner GC. Statistics in medicine. Plast Reconstr Surg. 2011 Jan;127(1):437-444. DOI: 10.1097/PRS.0b013e3181f95dd2.
Publication of the article:
«Bulletin of problems biology and medicine», 2023 Issue 3, 170, 244-247 pages, index UDC 618.15-007.44
